MCCF_ECOLX
ID MCCF_ECOLX Reviewed; 344 AA.
AC Q47511;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=Microcin C7 self-immunity protein MccF;
GN Name=mccF;
OS Escherichia coli.
OG Plasmid pMccC7.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=562;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8522520; DOI=10.1128/jb.177.24.7131-7140.1995;
RA Gonzalez-Pastor J.E., San Millan J.L., Castilla M.A., Moreno F.;
RT "Structure and organization of plasmid genes required to produce the
RT translation inhibitor microcin C7.";
RL J. Bacteriol. 177:7131-7140(1995).
CC -!- FUNCTION: Involved in specific self-immunity to microcin C7.
CC -!- INTERACTION:
CC Q47511; Q47511: mccF; NbExp=2; IntAct=EBI-15973002, EBI-15973002;
CC -!- SIMILARITY: Belongs to the peptidase S66 family. {ECO:0000305}.
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DR EMBL; X57583; CAA40814.1; -; Genomic_DNA.
DR RefSeq; WP_000973426.1; NZ_VRXN01000031.1.
DR PDB; 3TLA; X-ray; 1.20 A; A/B=2-344.
DR PDB; 3TLB; X-ray; 1.50 A; A/B=2-344.
DR PDB; 3TLC; X-ray; 1.30 A; A/B=2-344.
DR PDB; 3TLE; X-ray; 1.30 A; A/B=2-344.
DR PDB; 3TLG; X-ray; 1.50 A; A/B=2-344.
DR PDB; 3TLY; X-ray; 1.70 A; A/B=2-344.
DR PDB; 3TLZ; X-ray; 1.50 A; A/B=2-344.
DR PDB; 4IIX; X-ray; 1.23 A; A/B=2-344.
DR PDB; 4IIY; X-ray; 1.20 A; A/B=2-344.
DR PDBsum; 3TLA; -.
DR PDBsum; 3TLB; -.
DR PDBsum; 3TLC; -.
DR PDBsum; 3TLE; -.
DR PDBsum; 3TLG; -.
DR PDBsum; 3TLY; -.
DR PDBsum; 3TLZ; -.
DR PDBsum; 4IIX; -.
DR PDBsum; 4IIY; -.
DR AlphaFoldDB; Q47511; -.
DR SMR; Q47511; -.
DR DIP; DIP-60028N; -.
DR ChEMBL; CHEMBL3596082; -.
DR MEROPS; S66.003; -.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR GO; GO:0030153; P:bacteriocin immunity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.10740; -; 1.
DR Gene3D; 3.50.30.60; -; 1.
DR InterPro; IPR027461; Carboxypeptidase_A_C_sf.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR027478; LdcA_N.
DR InterPro; IPR040449; Peptidase_S66_N.
DR InterPro; IPR040921; Peptidase_S66C.
DR InterPro; IPR003507; S66_fam.
DR PANTHER; PTHR30237; PTHR30237; 1.
DR Pfam; PF02016; Peptidase_S66; 1.
DR Pfam; PF17676; Peptidase_S66C; 1.
DR PIRSF; PIRSF028757; LD-carboxypeptidase; 1.
DR SUPFAM; SSF141986; SSF141986; 1.
DR SUPFAM; SSF52317; SSF52317; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Bacteriocin immunity; Hydrolase; Plasmid.
FT CHAIN 1..344
FT /note="Microcin C7 self-immunity protein MccF"
FT /id="PRO_0000172840"
FT STRAND 18..22
FT /evidence="ECO:0007829|PDB:4IIY"
FT HELIX 28..31
FT /evidence="ECO:0007829|PDB:4IIY"
FT HELIX 33..45
FT /evidence="ECO:0007829|PDB:4IIY"
FT STRAND 49..52
FT /evidence="ECO:0007829|PDB:4IIY"
FT TURN 54..57
FT /evidence="ECO:0007829|PDB:4IIY"
FT STRAND 63..65
FT /evidence="ECO:0007829|PDB:4IIY"
FT HELIX 67..79
FT /evidence="ECO:0007829|PDB:4IIY"
FT STRAND 83..89
FT /evidence="ECO:0007829|PDB:4IIY"
FT HELIX 95..101
FT /evidence="ECO:0007829|PDB:4IIY"
FT HELIX 104..109
FT /evidence="ECO:0007829|PDB:4IIY"
FT STRAND 113..116
FT /evidence="ECO:0007829|PDB:4IIY"
FT HELIX 118..120
FT /evidence="ECO:0007829|PDB:4IIY"
FT HELIX 121..131
FT /evidence="ECO:0007829|PDB:4IIY"
FT STRAND 135..137
FT /evidence="ECO:0007829|PDB:4IIY"
FT HELIX 141..145
FT /evidence="ECO:0007829|PDB:4IIY"
FT HELIX 151..164
FT /evidence="ECO:0007829|PDB:4IIY"
FT STRAND 177..180
FT /evidence="ECO:0007829|PDB:4IIY"
FT STRAND 185..187
FT /evidence="ECO:0007829|PDB:4IIY"
FT STRAND 203..206
FT /evidence="ECO:0007829|PDB:4IIY"
FT STRAND 208..218
FT /evidence="ECO:0007829|PDB:4IIY"
FT HELIX 219..222
FT /evidence="ECO:0007829|PDB:4IIY"
FT TURN 223..227
FT /evidence="ECO:0007829|PDB:4IIY"
FT STRAND 239..243
FT /evidence="ECO:0007829|PDB:4IIY"
FT HELIX 249..261
FT /evidence="ECO:0007829|PDB:4IIY"
FT HELIX 264..266
FT /evidence="ECO:0007829|PDB:4IIY"
FT STRAND 269..274
FT /evidence="ECO:0007829|PDB:4IIY"
FT HELIX 288..296
FT /evidence="ECO:0007829|PDB:4IIY"
FT STRAND 303..308
FT /evidence="ECO:0007829|PDB:4IIY"
FT STRAND 310..314
FT /evidence="ECO:0007829|PDB:4IIY"
FT STRAND 318..327
FT /evidence="ECO:0007829|PDB:4IIY"
FT TURN 328..331
FT /evidence="ECO:0007829|PDB:4IIY"
FT STRAND 332..335
FT /evidence="ECO:0007829|PDB:4IIY"
SQ SEQUENCE 344 AA; 38361 MW; 759CEF7AB49E5C2D CRC64;
MMIQSHPLLA APLAVGDTIG FFSSSAPATV TAKNRFFRGV EFLQRKGFKL VSGKLTGKTD
FYRSGTIKER AQEFNELVYN PDITCIMSTI GGDNSNSLLP FLDYDAIIAN PKIIIGYSDT
TALLAGIYAK TGLITFYGPA LIPSFGEHPP LVDITYESFI KILTRKQSGI YTYTLPEKWS
DESINWNENK ILRPKKLYKN NCAFYGSGKV EGRVIGGNLN TLTGIWGSEW MPEILNGDIL
FIEDSRKSIA TIERLFSMLK LNRVFDKVSA IILGKHELFD CAGSKRRPYE VLTEVLDGKQ
IPVLDGFDCS HTHPMLTLPL GVKLAIDFDN KNISITEQYL STEK
