ID   ARGP_YERPS              Reviewed;         302 AA.
AC   Q666Q6;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=HTH-type transcriptional regulator ArgP {ECO:0000255|HAMAP-Rule:MF_00513};
GN   Name=argP {ECO:0000255|HAMAP-Rule:MF_00513}; Synonyms=iciA;
GN   OrderedLocusNames=YPTB3191;
OS   Yersinia pseudotuberculosis serotype I (strain IP32953).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=273123;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IP32953;
RX   PubMed=15358858; DOI=10.1073/pnas.0404012101;
RA   Chain P.S.G., Carniel E., Larimer F.W., Lamerdin J., Stoutland P.O.,
RA   Regala W.M., Georgescu A.M., Vergez L.M., Land M.L., Motin V.L.,
RA   Brubaker R.R., Fowler J., Hinnebusch J., Marceau M., Medigue C.,
RA   Simonet M., Chenal-Francisque V., Souza B., Dacheux D., Elliott J.M.,
RA   Derbise A., Hauser L.J., Garcia E.;
RT   "Insights into the evolution of Yersinia pestis through whole-genome
RT   comparison with Yersinia pseudotuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:13826-13831(2004).
CC   -!- FUNCTION: Controls the transcription of genes involved in arginine and
CC       lysine metabolism. {ECO:0000255|HAMAP-Rule:MF_00513}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00513}.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; BX936398; CAH22429.1; -; Genomic_DNA.
DR   RefSeq; WP_002209958.1; NZ_CP009712.1.
DR   AlphaFoldDB; Q666Q6; -.
DR   SMR; Q666Q6; -.
DR   PRIDE; Q666Q6; -.
DR   EnsemblBacteria; CAH22429; CAH22429; YPTB3191.
DR   GeneID; 66844378; -.
DR   KEGG; ypo:BZ17_3420; -.
DR   KEGG; yps:YPTB3191; -.
DR   PATRIC; fig|273123.14.peg.3589; -.
DR   OMA; QQWKLDS; -.
DR   Proteomes; UP000001011; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   HAMAP; MF_00513; HTH_type_ArgP; 1.
DR   InterPro; IPR017685; ArgP.
DR   InterPro; IPR023490; ArgP_Gammaproteobact.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   TIGRFAMs; TIGR03298; argP; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..302
FT                   /note="HTH-type transcriptional regulator ArgP"
FT                   /id="PRO_0000258620"
FT   DOMAIN          4..60
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00513"
FT   DNA_BIND        21..40
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00513"
SQ   SEQUENCE   302 AA;  33892 MW;  B887E1812782097C CRC64;
     MKRPDYRTLQ ALDAVIRERG FERAAQKLCI TQSAVSQRIK QLENLFGQPL LVRTVPPRPT
     EQGQKLLALL HQVELLEEEW LGNDNGVDTP LLLSLAVNAD SLATWLLPAL KPVLADLPIR
     LNLQVEDETR TQERLRRGEV VGAVSIQPQP LPSCLVDQLG ALDYLFVASK AFAERYFPNG
     VTRSALLKAP AVAFDHLDDM HQAFLQQNFD LSPGSVPCHI VNSSEAFVQL ARQGTTCCMI
     PHLQIEKELA SGELIDLTPG LLQRRMLFWH RFAPESRTMR KVTDALLSYG RQVLRQDSFI
     GQ