ID   MCH1_CANGA              Reviewed;         489 AA.
AC   Q6FWD4;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Probable transporter MCH1;
GN   Name=MCH1; OrderedLocusNames=CAGL0D01056g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Probable transporter. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR380950; CAG58371.1; -; Genomic_DNA.
DR   RefSeq; XP_445460.1; XM_445460.1.
DR   AlphaFoldDB; Q6FWD4; -.
DR   STRING; 5478.XP_445460.1; -.
DR   EnsemblFungi; CAG58371; CAG58371; CAGL0D01056g.
DR   GeneID; 2887171; -.
DR   KEGG; cgr:CAGL0D01056g; -.
DR   CGD; CAL0128363; CAGL0D01056g.
DR   VEuPathDB; FungiDB:CAGL0D01056g; -.
DR   eggNOG; ENOG502QTNE; Eukaryota.
DR   HOGENOM; CLU_012596_3_0_1; -.
DR   InParanoid; Q6FWD4; -.
DR   OMA; WRGPGGW; -.
DR   Proteomes; UP000002428; Chromosome D.
DR   GO; GO:0000329; C:fungal-type vacuole membrane; IEA:EnsemblFungi.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport; Vacuole.
FT   CHAIN           1..489
FT                   /note="Probable transporter MCH1"
FT                   /id="PRO_0000084869"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        92..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        132..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        163..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        202..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        279..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        307..327
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        351..371
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        388..408
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        421..441
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        462..482
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        123
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        450
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   489 AA;  54363 MW;  0831C3709803E924 CRC64;
     MALSSIEHYL SYHLRVLLPQ VLSSKSSHNI AYIFALFAAI TSGFVSLISL YAQPWQEHLS
     YSSWQINMIV TVINMGMYLT PPILGIIADI HGPITLSLSS VLGFIPSYAY LAYTFHRDHS
     FTNESDGSFT PTLVCFFIIG VATSGLYFSA LITCAKLFPG TKLLSISIPT TCYGLSSLIG
     SQFLRVKYFH PVDYPYLDLG RVFKAFAWIY TVIGVMIWIA TSKVAQIQHE ADIMEEQDRM
     AEPSDNDVEN HYDDNEQSRL LHATHAQQMT LMKVFRDPVL YIFGATIFCA LGPLEMFIAN
     MGSLTNVLAG GHEPAMSSAL LSIYALTSTL TRLGTGLTVD YFNKRQLSVK WILLLFLVVG
     LVTQGKIYML SMSSLDHSHM VTINRKLFYI GIMQGIAYGG LFTIYPTITL MVWGEKMFGT
     AYGTLMIAPA LGSALSCLIY ADVYDSECAN STTRSCIAPV YETTALEFCA AILLTVVVTV
     LWRKRRTHI