MCH_CARSF
ID MCH_CARSF Reviewed; 71 AA.
AC O62691;
DT 15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 25-MAY-2022, entry version 77.
DE RecName: Full=Pro-MCH;
DE Flags: Precursor; Fragment;
GN Name=PMCH;
OS Carlito syrichta (Philippine tarsier) (Tarsius syrichta).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Tarsiiformes; Tarsiidae;
OC Carlito.
OX NCBI_TaxID=1868482;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9491616; DOI=10.1093/oxfordjournals.molbev.a025915;
RA Viale A., Ortola C., Richard F., Vernier P., Presse F., Schilling S.,
RA Dutrillaux B., Nahon J.-L.;
RT "Emergence of a brain-expressed variant melanin-concentrating hormone gene
RT during higher primate evolution: a gene 'in search of a function'.";
RL Mol. Biol. Evol. 15:196-214(1998).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the melanin-concentrating hormone family.
CC {ECO:0000305}.
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DR EMBL; AF029399; AAC05252.1; -; Genomic_DNA.
DR AlphaFoldDB; O62691; -.
DR STRING; 1868482.ENSTSYP00000002686; -.
DR HOGENOM; CLU_1610172_0_0_1; -.
DR Proteomes; UP000189704; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0045202; C:synapse; IEA:GOC.
DR GO; GO:0030354; F:melanin-concentrating hormone activity; IEA:InterPro.
DR GO; GO:0007268; P:chemical synaptic transmission; IEA:InterPro.
DR InterPro; IPR005456; Prepro-melanin_conc_hormone.
DR PANTHER; PTHR12091; PTHR12091; 1.
PE 3: Inferred from homology;
KW Reference proteome; Secreted; Signal.
FT SIGNAL <1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..>71
FT /note="Pro-MCH"
FT /id="PRO_0000019111"
FT NON_TER 1
FT NON_TER 71
SQ SEQUENCE 71 AA; 7945 MW; 0ADD578973920835 CRC64;
AKMSLSSYIL ILTLVLFSQG ILLSASKSIR NLEDDMVFNT FRLGKAFQKE DTAEKSVVAP
SLEQYKNDEN S