ID   MCH_PANTR               Reviewed;          71 AA.
AC   O62689;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Pro-MCH;
DE   Flags: Precursor; Fragment;
GN   Name=PMCH;
OS   Pan troglodytes (Chimpanzee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
OX   NCBI_TaxID=9598;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9491616; DOI=10.1093/oxfordjournals.molbev.a025915;
RA   Viale A., Ortola C., Richard F., Vernier P., Presse F., Schilling S.,
RA   Dutrillaux B., Nahon J.-L.;
RT   "Emergence of a brain-expressed variant melanin-concentrating hormone gene
RT   during higher primate evolution: a gene 'in search of a function'.";
RL   Mol. Biol. Evol. 15:196-214(1998).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the melanin-concentrating hormone family.
CC       {ECO:0000305}.
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DR   EMBL; AF029397; AAC05250.1; -; Genomic_DNA.
DR   AlphaFoldDB; O62689; -.
DR   STRING; 9598.ENSPTRP00000009113; -.
DR   PaxDb; O62689; -.
DR   eggNOG; ENOG502RZ12; Eukaryota.
DR   InParanoid; O62689; -.
DR   Proteomes; UP000002277; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0045202; C:synapse; IEA:GOC.
DR   GO; GO:0030354; F:melanin-concentrating hormone activity; IEA:InterPro.
DR   GO; GO:0031777; F:type 1 melanin-concentrating hormone receptor binding; IBA:GO_Central.
DR   GO; GO:0007268; P:chemical synaptic transmission; IEA:InterPro.
DR   InterPro; IPR005456; Prepro-melanin_conc_hormone.
DR   PANTHER; PTHR12091; PTHR12091; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          <1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..>71
FT                   /note="Pro-MCH"
FT                   /id="PRO_0000019110"
FT   NON_TER         1
FT   NON_TER         71
SQ   SEQUENCE   71 AA;  7942 MW;  CF743E9D9D70BB71 CRC64;
     AKMNLSSYIL ILTFSLFSQG ILLSASKSIR NSDDDMVFNT FRLGKAFQKE DTAEKSVIAP
     SLEEYKNDES S