MCM9_ORYSI
ID MCM9_ORYSI Reviewed; 674 AA.
AC B8B406;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 03-MAR-2009, sequence version 1.
DT 03-AUG-2022, entry version 67.
DE RecName: Full=Probable DNA helicase MCM9;
DE EC=3.6.4.12;
DE AltName: Full=Minichromosome maintenance 9;
GN Name=MCM9; ORFNames=OsI_22179;
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- FUNCTION: Probable DNA helicase that may play a role in DNA repair
CC during meiosis. {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the MCM family. {ECO:0000305}.
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DR EMBL; CM000131; EEC80238.1; -; Genomic_DNA.
DR AlphaFoldDB; B8B406; -.
DR SMR; B8B406; -.
DR STRING; 39946.B8B406; -.
DR EnsemblPlants; BGIOSGA021655-TA; BGIOSGA021655-PA; BGIOSGA021655.
DR Gramene; BGIOSGA021655-TA; BGIOSGA021655-PA; BGIOSGA021655.
DR HOGENOM; CLU_000995_7_2_1; -.
DR OMA; RLSAKWS; -.
DR Proteomes; UP000007015; Chromosome 6.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR Gene3D; 2.40.50.140; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR001208; MCM_dom.
DR InterPro; IPR041562; MCM_lid.
DR InterPro; IPR027925; MCM_N.
DR InterPro; IPR033762; MCM_OB.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11630; PTHR11630; 1.
DR Pfam; PF00493; MCM; 1.
DR Pfam; PF17855; MCM_lid; 1.
DR Pfam; PF14551; MCM_N; 1.
DR Pfam; PF17207; MCM_OB; 1.
DR PRINTS; PR01657; MCMFAMILY.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00350; MCM; 1.
DR SUPFAM; SSF50249; SSF50249; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS50051; MCM_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; DNA damage; DNA repair; DNA-binding; Helicase; Hydrolase;
KW Meiosis; Metal-binding; Nucleotide-binding; Nucleus; Reference proteome;
KW Zinc; Zinc-finger.
FT CHAIN 1..674
FT /note="Probable DNA helicase MCM9"
FT /id="PRO_0000426006"
FT DOMAIN 318..521
FT /note="MCM"
FT ZN_FING 165..198
FT /note="C4-type"
FT /evidence="ECO:0000255"
FT MOTIF 497..500
FT /note="Arginine finger"
FT BINDING 368..375
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000250"
SQ SEQUENCE 674 AA; 74689 MW; 941CAA652C53485B CRC64;
MPPPAEEFAV DDLDEFESRL DSFLNRFHAD DLRRILLPDP DGKLHFPLVI DFAELLEFDP
EVAHQLYDYP KDVLELFDAA AQRALDKFDA AARRADKRKA GDEPMEKKFV HVRVNTSGSP
LECPEASPSI GKVRVKHRGT LLTLKGTVIR SGGVKMIEGE RKYQCRKCKC RFTVHPELEA
GNRITLPASC KSKSAKGCGG ANFQLIEDSI TCHDYQEIKI QENIQLLGVG SIPRSMPIIL
MDDLVDIVKA GDDVVVTGRL SAKWSPDIKD VRSNLDPMLI ANFVRRTNEL KSDLDIPVEI
INKFEEFWAA SRATPLKGRN SILKGICPQI YGLFTVKLAV ALTLIGGVQH VDASGTKVRG
EPHMLLVGDP GTGKSQFLKF AAKLSNRSVI TTGLGSTSAG LTVTAVKDGG EWMLEAGALV
LADGGLCCID EFDSMREHDR TTIHEAMEQQ TISIAKAGLV TTLNTRTTVF GATNPKGQYD
PNESLSVNTT LSGPLLSRFD IVLVLLDTKN KKWDKIVSSH ILAENTEEKK GKTSDPEVMW
TLSMLRRYIH YVKQHFKPVL TKEAERVISS YYQRQRQSGT RNAARTTVRM LESLIRLAQA
HARLMFRNDV TKLDAIAAIL CIESSMTTSA IVDTAGNALH SNFTENPDQE CILKCDSIAY
LSKNIKYLTD EISN
