MCM9_ORYSJ
ID MCM9_ORYSJ Reviewed; 674 AA.
AC Q69QA6; A0A0P0WUD0;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 13-SEP-2004, sequence version 1.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Probable DNA helicase MCM9;
DE EC=3.6.4.12;
DE AltName: Full=Minichromosome maintenance 9;
DE Short=OsMCM9;
GN Name=MCM9; OrderedLocusNames=Os06g0218500, LOC_Os06g11500;
GN ORFNames=P0436F11.6, P0644A02.30;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [5]
RP GENE FAMILY.
RX PubMed=17556508; DOI=10.1104/pp.107.101105;
RA Shultz R.W., Tatineni V.M., Hanley-Bowdoin L., Thompson W.F.;
RT "Genome-wide analysis of the core DNA replication machinery in the higher
RT plants Arabidopsis and rice.";
RL Plant Physiol. 144:1697-1714(2007).
CC -!- FUNCTION: Probable DNA helicase that may play a role in DNA repair
CC during meiosis. {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the MCM family. {ECO:0000305}.
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DR EMBL; AP003488; BAD37231.1; -; Genomic_DNA.
DR EMBL; AP005425; BAD36103.1; -; Genomic_DNA.
DR EMBL; AP008212; BAF19072.1; -; Genomic_DNA.
DR EMBL; AP014962; BAS96811.1; -; Genomic_DNA.
DR EMBL; AK100667; BAG94707.1; -; mRNA.
DR RefSeq; XP_015643699.1; XM_015788213.1.
DR RefSeq; XP_015643700.1; XM_015788214.1.
DR RefSeq; XP_015643701.1; XM_015788215.1.
DR AlphaFoldDB; Q69QA6; -.
DR SMR; Q69QA6; -.
DR STRING; 4530.OS06T0218500-01; -.
DR PaxDb; Q69QA6; -.
DR PRIDE; Q69QA6; -.
DR EnsemblPlants; Os06t0218500-01; Os06t0218500-01; Os06g0218500.
DR EnsemblPlants; Os06t0218500-02; Os06t0218500-02; Os06g0218500.
DR GeneID; 4340503; -.
DR Gramene; Os06t0218500-01; Os06t0218500-01; Os06g0218500.
DR Gramene; Os06t0218500-02; Os06t0218500-02; Os06g0218500.
DR KEGG; osa:4340503; -.
DR eggNOG; KOG0477; Eukaryota.
DR HOGENOM; CLU_000995_7_2_1; -.
DR InParanoid; Q69QA6; -.
DR OMA; RLSAKWS; -.
DR OrthoDB; 266497at2759; -.
DR Proteomes; UP000000763; Chromosome 6.
DR Proteomes; UP000059680; Chromosome 6.
DR Genevisible; Q69QA6; OS.
DR GO; GO:0042555; C:MCM complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003678; F:DNA helicase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003697; F:single-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IBA:GO_Central.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR Gene3D; 2.40.50.140; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR001208; MCM_dom.
DR InterPro; IPR041562; MCM_lid.
DR InterPro; IPR027925; MCM_N.
DR InterPro; IPR033762; MCM_OB.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11630; PTHR11630; 1.
DR Pfam; PF00493; MCM; 1.
DR Pfam; PF17855; MCM_lid; 1.
DR Pfam; PF14551; MCM_N; 1.
DR Pfam; PF17207; MCM_OB; 1.
DR PRINTS; PR01657; MCMFAMILY.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00350; MCM; 1.
DR SUPFAM; SSF50249; SSF50249; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS50051; MCM_2; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; DNA damage; DNA repair; DNA-binding; Helicase; Hydrolase;
KW Meiosis; Metal-binding; Nucleotide-binding; Nucleus; Reference proteome;
KW Zinc; Zinc-finger.
FT CHAIN 1..674
FT /note="Probable DNA helicase MCM9"
FT /id="PRO_0000426005"
FT DOMAIN 318..521
FT /note="MCM"
FT ZN_FING 165..198
FT /note="C4-type"
FT /evidence="ECO:0000255"
FT MOTIF 497..500
FT /note="Arginine finger"
FT BINDING 368..375
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000250"
SQ SEQUENCE 674 AA; 74699 MW; 4ADC31DA93E2E855 CRC64;
MPPPAEEFAV DDLDEFESRL DSFLNRFHAD DLRRILLPFP DGKLHFPLVI DFAELLEFDP
EVAHQLYDYP KDVLELFDAA AQRALDKFDA AARRADKRKA GDETMEKKFV HVRVNTSGSA
LECPEASPSI GKVRVKHRGT LLTLKGTVIR SGGVKMIEGE RKYQCRKCKC RFTVHPELEA
GNRITLPASC KSKSAKGCGG ANFQLIEDSI TCHDYQEIKI QENIQLLGVG SIPRSMPIIL
MDDLVDIVKA GDDVVVTGRL SAKWSPDIKD VRSNLDPMLI ANFVRRTNEL KSDLDIPVEI
INKFEEFWAA SRATPLKGRN SILKGICPQI YGLFTVKLAV ALTLIGGVQH VDASGTKVRG
EPHMLLVGDP GTGKSQFLKF AAKLSNRSVI TTGLGSTSAG LTVTAVKDGG EWMLEAGALV
LADGGLCCID EFDSMREHDR TTIHEAMEQQ TISIAKAGLV TTLNTRTTVF GATNPKGQYD
PNESLSVNTT LSGPLLSRFD IVLVLLDTKN KKWDKIVSSH ILAENTEEKK GKTSDPEVMW
TLSMLRRYIH YVKQHFKPVL TKEAERVISS YYQRQRQSGT RNAARTTVRM LESLIRLAQA
HARLMFRNDV TKLDAIAAIL CIESSMTTSA IVDTAGNALH SNFTENPDQE CILKCDSIAY
LSKNIKYLTD EISN
