ID   MCP2_SCHPO              Reviewed;         703 AA.
AC   O74438;
DT   16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Meiotic coiled-coil protein 2;
GN   Name=mcp2; ORFNames=SPCC1682.08c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=17509158; DOI=10.1186/1747-1028-2-14;
RA   Ohtaka A., Saito T.T., Okuzaki D., Nojima H.;
RT   "Meiosis specific coiled-coil proteins in Shizosaccharomyces pombe.";
RL   Cell Div. 2:14-14(2007).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
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DR   EMBL; AB189990; BAD42852.2; -; Genomic_DNA.
DR   EMBL; CU329672; CAA20674.1; -; Genomic_DNA.
DR   PIR; T41065; T41065.
DR   RefSeq; NP_587801.1; NM_001022794.2.
DR   AlphaFoldDB; O74438; -.
DR   SMR; O74438; -.
DR   BioGRID; 275709; 42.
DR   STRING; 4896.SPCC1682.08c.1; -.
DR   SwissPalm; O74438; -.
DR   PaxDb; O74438; -.
DR   EnsemblFungi; SPCC1682.08c.1; SPCC1682.08c.1:pep; SPCC1682.08c.
DR   GeneID; 2539137; -.
DR   KEGG; spo:SPCC1682.08c; -.
DR   PomBase; SPCC1682.08c; mcp2.
DR   VEuPathDB; FungiDB:SPCC1682.08c; -.
DR   eggNOG; KOG1488; Eukaryota.
DR   HOGENOM; CLU_009803_1_0_1; -.
DR   InParanoid; O74438; -.
DR   OMA; FENCVEK; -.
DR   PhylomeDB; O74438; -.
DR   PRO; PR:O74438; -.
DR   Proteomes; UP000002485; Chromosome III.
DR   GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR   GO; GO:0000932; C:P-body; EXP:PomBase.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IBA:GO_Central.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; ISO:PomBase.
DR   GO; GO:0010608; P:post-transcriptional regulation of gene expression; IBA:GO_Central.
DR   CDD; cd07920; Pumilio; 1.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR033133; PUM-HD.
DR   InterPro; IPR033712; Pumilio_RNA-bd.
DR   InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR   Pfam; PF00806; PUF; 8.
DR   SMART; SM00025; Pumilio; 8.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   PROSITE; PS50302; PUM; 9.
DR   PROSITE; PS50303; PUM_HD; 1.
PE   4: Predicted;
KW   Meiosis; Reference proteome; Repeat; RNA-binding.
FT   CHAIN           1..703
FT                   /note="Meiotic coiled-coil protein 2"
FT                   /id="PRO_0000234662"
FT   DOMAIN          331..686
FT                   /note="PUM-HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00318"
FT   REPEAT          361..396
FT                   /note="Pumilio 1"
FT   REPEAT          397..432
FT                   /note="Pumilio 2"
FT   REPEAT          433..468
FT                   /note="Pumilio 3"
FT   REPEAT          469..504
FT                   /note="Pumilio 4"
FT   REPEAT          509..544
FT                   /note="Pumilio 5"
FT   REPEAT          545..580
FT                   /note="Pumilio 6"
FT   REPEAT          581..616
FT                   /note="Pumilio 7"
FT   REPEAT          625..660
FT                   /note="Pumilio 8"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          245..265
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          284..309
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..19
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   703 AA;  78641 MW;  3379192DCF0BC0E0 CRC64;
     MQSIDLRLPS TSANHSISES LEHSKSELNE LSNVSESESY FDITKKLHAL STVVQRQQRE
     IDNQKRDLCT KTKHIEELQT LLSNANIMSD GASSQNDAFA HNPSTSVSVE LVRPVVGTKK
     HAVYATSAPK SMSLQDSLSV PSATALADVS SSLNYSRKLS SNSIKSTNAP VFGTAVKNVT
     GENILSASSS EENLNSNRNG DPKFRFSVSP WISSSNFNPY EASLANFQSD NCKLKSHNSL
     PSIRTNVRYS NSKPSTPLSP EDVDLGTYTV KNRDSWSNEV NLSASTNNLS TNTSGTLKPY
     SLSSSRSSSY SKGVNSAASL QSIWETMNNS NPSVIPESTS SREPAARYRK ISERNAVYDW
     NVIIDKIIVS NDQQSSIFLQ QKLKISSYDM KQNIVDSIIS QIHPLMLNRF GNFLVQRCFE
     HGTAPQIRQM GSAMLGNMLK LATDPFGCHV VQKAIDNVTE DIKLAMMDEL FLTIDVTIMH
     HYACHVWQKL FETQWYEYPV NVMNRVNNAL RGKWHEVAVG ENGSLVVQNM FENCVEKDKR
     ECIEEIIFHL DGIARGQWGN WVVQHMVENG QGEDLKRVID ALLNRAVEFS IDQFASKVIE
     KAIKSGPKNF ISLYLKQITN ARVDRTRQPL IDIASDQYGN YLIQQIIQLG QPAEKNLVIT
     HIKKHMVSLR GSKYGQKVAY LVEKWNSQKQ VSSVINYNCN TDL