ID   MCP3_SCHPO              Reviewed;         952 AA.
AC   Q9UTR7;
DT   01-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Meiotic coiled-coil protein 3;
DE   AltName: Full=Meiotically up-regulated gene 7 protein;
GN   Name=mcp3; Synonyms=mug7; ORFNames=SPAC1006.04c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=17509158; DOI=10.1186/1747-1028-2-14;
RA   Ohtaka A., Saito T.T., Okuzaki D., Nojima H.;
RT   "Meiosis specific coiled-coil proteins in Shizosaccharomyces pombe.";
RL   Cell Div. 2:14-14(2007).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [3]
RP   FUNCTION IN MEIOSIS.
RX   PubMed=16303567; DOI=10.1016/j.cub.2005.10.038;
RA   Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L.,
RA   Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P.,
RA   Smith G.R., Moreno S.;
RT   "A large-scale screen in S. pombe identifies seven novel genes required for
RT   critical meiotic events.";
RL   Curr. Biol. 15:2056-2062(2005).
RN   [4]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Has a role in meiosis. {ECO:0000269|PubMed:16303567}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
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DR   EMBL; AB189989; BAD42851.1; -; Genomic_DNA.
DR   EMBL; CU329670; CAB60234.1; -; Genomic_DNA.
DR   PIR; T50451; T50451.
DR   RefSeq; NP_594851.1; NM_001020280.2.
DR   AlphaFoldDB; Q9UTR7; -.
DR   SMR; Q9UTR7; -.
DR   STRING; 4896.SPAC1006.04c.1; -.
DR   PaxDb; Q9UTR7; -.
DR   PRIDE; Q9UTR7; -.
DR   EnsemblFungi; SPAC1006.04c.1; SPAC1006.04c.1:pep; SPAC1006.04c.
DR   GeneID; 2543146; -.
DR   KEGG; spo:SPAC1006.04c; -.
DR   PomBase; SPAC1006.04c; mcp3.
DR   VEuPathDB; FungiDB:SPAC1006.04c; -.
DR   HOGENOM; CLU_309527_0_0_1; -.
DR   InParanoid; Q9UTR7; -.
DR   OMA; AISEMHA; -.
DR   PhylomeDB; Q9UTR7; -.
DR   PRO; PR:Q9UTR7; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Coiled coil; Cytoplasm; Meiosis; Reference proteome.
FT   CHAIN           1..952
FT                   /note="Meiotic coiled-coil protein 3"
FT                   /id="PRO_0000096289"
FT   COILED          283..611
FT                   /evidence="ECO:0000255"
FT   COILED          684..716
FT                   /evidence="ECO:0000255"
FT   COILED          839..942
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   952 AA;  109870 MW;  B279C65CDCC1D8D6 CRC64;
     MTKETHENHL RTHNGIFPVS LLSTQARQLL NFKLKSPSYY LLNSFKLLVK SEGNNQSTTA
     DVTLTKSPNA YHASSAREEK DLQVSRRDTC FYCSRKIIKC ICNEEHVGIE SVQLKLILLL
     CQNLPNVTTN AKKYFSSLAD GHNFTLTLYK FSLDNQTFSQ LLSRFKSFAT LTELLQVHNV
     MLQVNFSFQA RQLNTEIQLR RCHSLEKTWK FLFGDYELPD VLKDMESSNS DWSDTSLKRI
     AYLCSLVEEL KLHSSIMNDK YVCLVSKHNN ALEDKFNSEA ARQLLQKSLS IVASNLKQAE
     NKTISYEEKL SIAQNSINEI QTQNRDLKLE TEKLQDQIKA LLERNQSLQE ALETVKNDEK
     NLREMNANYE TEMKEARQKL NNKEALISHY DDDFRAKELK ISRLSESLRE KAGLLEFQSS
     VSEQRDLLYQ EQIQSSIKDM ENVFRKNEYL MEELNELKNN LEVESSKVLR LDEEMKCLKD
     EQLSQFDTVF SLTDERDGLQ KDLKNTKGNL DDEIGRSAFL KSQIRDQELT IEKLHDSLET
     LSQTNNSLQC EISEKNAELN SVNSKLSEGR AHLETANKEN EILKQQLELS ESKLASLLNS
     YQSFINKKEH LYSFLQLVEP SFAKSDSSNA TESQISESVR KGISIFNLLF IVYKNVCSQA
     GINPSTKLED LDEHTLSDEL TYITKKFVQK DQEYQTKEIE LRNYKITLQS LLEDKLIGVN
     TDCRSPSCSD FEQLGQESEN NTSISGRVSK LVKSFNDSSS ISNNTKISIT KSPSGEKVSV
     FKEMSDIALR DMDKNRKLLG ENVDVRNIVV QKDESLNIDL QNNAVVPELH FKEGMVYDSL
     ENAYTYLAES KRMLANELQM KQEDLEKVIL ELEAYKEIFL EEKQIPCEEF MPGKNAKSEK
     SLRSVFQEQL MRETKRVRKL EKVNSELKLH CFELSERLRE REHTLQQTFG DK