MCP_IIV3
ID MCP_IIV3 Reviewed; 466 AA.
AC Q197E6;
DT 16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT 11-JUL-2006, sequence version 1.
DT 23-FEB-2022, entry version 47.
DE RecName: Full=Major capsid protein;
DE Short=MCP;
GN Name=MCP; ORFNames=IIV3-014L;
OS Invertebrate iridescent virus 3 (IIV-3) (Mosquito iridescent virus).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC Pimascovirales; Iridoviridae; Betairidovirinae; Chloriridovirus.
OX NCBI_TaxID=345201;
OH NCBI_TaxID=7163; Aedes vexans (Inland floodwater mosquito) (Culex vexans).
OH NCBI_TaxID=42431; Culex territans.
OH NCBI_TaxID=332058; Culiseta annulata.
OH NCBI_TaxID=310513; Ochlerotatus sollicitans (eastern saltmarsh mosquito).
OH NCBI_TaxID=329105; Ochlerotatus taeniorhynchus (Black salt marsh mosquito) (Aedes taeniorhynchus).
OH NCBI_TaxID=7183; Psorophora ferox.
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16912294; DOI=10.1128/jvi.00464-06;
RA Delhon G., Tulman E.R., Afonso C.L., Lu Z., Becnel J.J., Moser B.A.,
RA Kutish G.F., Rock D.L.;
RT "Genome of invertebrate iridescent virus type 3 (mosquito iridescent
RT virus).";
RL J. Virol. 80:8439-8449(2006).
CC -!- FUNCTION: Major capsid protein that self assembles to form an
CC icosahedral capsid. Represents around 50% of the total virion protein
CC mass (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Homotrimer. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the NCLDV major capsid protein family.
CC {ECO:0000305}.
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DR EMBL; DQ643392; ABF82044.1; -; Genomic_DNA.
DR RefSeq; YP_654586.1; NC_008187.1.
DR SMR; Q197E6; -.
DR GeneID; 4156263; -.
DR KEGG; vg:4156263; -.
DR Proteomes; UP000001358; Genome.
DR GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 2.70.9.20; -; 1.
DR InterPro; IPR031654; Capsid_N.
DR InterPro; IPR007542; MCP_C.
DR InterPro; IPR038519; MCP_C_sf.
DR InterPro; IPR016112; VP_dsDNA_II.
DR Pfam; PF16903; Capsid_N; 1.
DR Pfam; PF04451; Capsid_NCLDV; 1.
DR SUPFAM; SSF49749; SSF49749; 2.
PE 3: Inferred from homology;
KW Capsid protein; Late protein; Reference proteome; Virion.
FT CHAIN 1..466
FT /note="Major capsid protein"
FT /id="PRO_0000377514"
SQ SEQUENCE 466 AA; 50988 MW; 185217725541C253 CRC64;
MSSSITSGFI DLATVDEIEK YMYGLPDDGV SMAHTLTYFV REFKKSTWFT QVPVPLSRST
GTSDFGQNWS VSISRAGDYL LQTWLRVTIP QVTLAATATP ATLSLRWTRN LMHNLIREIT
ISFNDLVGSR LDNYFLDMWS AFTTPASKRN GYDNMIGNIS TLTDPVGPGG SLGHTGGTVL
NLPISLFFTR DTGVSLPTAA LPYNEIQLNF SMRDWKDLLI LTDTAITTGN PYQTIDVSKH
LGGVAPSLSN VQVWANYAIV SNVERKKMGC GVRDILIEQV QTAPRQNYTP STNPMPSFDI
RFSHAVKVLF FAVRNKTSAA EWSNYGTSSP VVSGTSVNYE PSGSFDPIAT TTLIYENSNR
LGTMGSDYYS LVSPWYHAPT IPSFIGYHMY SYSLNFFDLD PMGSTNYGKL TNVSIVPHAS
DAAVKASTGA GDGAGANYNQ SYEFIVMAVN NNIVRISGGC LGFPVL