ID   MCP_IIV6                Reviewed;         467 AA.
AC   Q05815;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2002, sequence version 2.
DT   23-FEB-2022, entry version 87.
DE   RecName: Full=Major capsid protein;
DE            Short=MCP;
DE   AltName: Full=P50;
GN   Name=MCP; ORFNames=IIV-6 274L;
OS   Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Pimascovirales; Iridoviridae; Betairidovirinae; Iridovirus.
OX   NCBI_TaxID=176652;
OH   NCBI_TaxID=6997; Acheta domesticus (House cricket).
OH   NCBI_TaxID=168631; Chilo suppressalis (Asiatic rice borer moth).
OH   NCBI_TaxID=6999; Gryllus bimaculatus (Two-spotted cricket).
OH   NCBI_TaxID=58607; Gryllus campestris.
OH   NCBI_TaxID=7108; Spodoptera frugiperda (Fall armyworm).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8492091; DOI=10.1099/0022-1317-74-5-873;
RA   Stohwasser R., Raab K., Schnitzler P., Janssen W., Darai G.;
RT   "Identification of the gene encoding the major capsid protein of insect
RT   iridescent virus type 6 by polymerase chain reaction.";
RL   J. Gen. Virol. 74:873-879(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11448171; DOI=10.1006/viro.2001.0963;
RA   Jakob N.J., Mueller K., Bahr U., Darai G.;
RT   "Analysis of the first complete DNA sequence of an invertebrate iridovirus:
RT   coding strategy of the genome of Chilo iridescent virus.";
RL   Virology 286:182-196(2001).
RN   [3]
RP   GENOME REANNOTATION.
RX   PubMed=17239238; DOI=10.1186/1743-422x-4-11;
RA   Eaton H.E., Metcalf J., Penny E., Tcherepanov V., Upton C., Brunetti C.R.;
RT   "Comparative genomic analysis of the family Iridoviridae: re-annotating and
RT   defining the core set of iridovirus genes.";
RL   Virol. J. 4:11-11(2007).
RN   [4]
RP   STRUCTURE BY ELECTRON MICROSCOPY OF THE CAPSID.
RX   PubMed=19027752; DOI=10.1016/j.jmb.2008.11.002;
RA   Yan X., Yu Z., Zhang P., Battisti A.J., Holdaway H.A., Chipman P.R.,
RA   Bajaj C., Bergoin M., Rossmann M.G., Baker T.S.;
RT   "The capsid proteins of a large, icosahedral dsDNA virus.";
RL   J. Mol. Biol. 385:1287-1299(2009).
CC   -!- FUNCTION: Major capsid protein that self assembles to form an
CC       icosahedral capsid with a T=147 symmetry. Represents around 50% of the
CC       total virion protein mass.
CC   -!- SUBUNIT: Homotrimer. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the NCLDV major capsid protein family.
CC       {ECO:0000305}.
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DR   EMBL; AF303741; AAK82135.1; -; Genomic_DNA.
DR   PIR; JQ2215; JQ2215.
DR   RefSeq; NP_149737.1; NC_003038.1.
DR   SMR; Q05815; -.
DR   GeneID; 1733341; -.
DR   KEGG; vg:1733341; -.
DR   Proteomes; UP000001359; Genome.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   Gene3D; 2.70.9.20; -; 1.
DR   InterPro; IPR031654; Capsid_N.
DR   InterPro; IPR007542; MCP_C.
DR   InterPro; IPR038519; MCP_C_sf.
DR   InterPro; IPR016112; VP_dsDNA_II.
DR   Pfam; PF16903; Capsid_N; 1.
DR   Pfam; PF04451; Capsid_NCLDV; 1.
DR   SUPFAM; SSF49749; SSF49749; 2.
PE   1: Evidence at protein level;
KW   Capsid protein; Late protein; Reference proteome; Virion.
FT   CHAIN           1..467
FT                   /note="Major capsid protein"
FT                   /id="PRO_0000222381"
FT   CONFLICT        328
FT                   /note="S -> Y (in Ref. 1)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        331
FT                   /note="I -> L (in Ref. 1)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   467 AA;  51322 MW;  5A81E1E79D3B41A6 CRC64;
     MSISSSNVTS GFIDIATKDE IEKYMYGGKT STAYFVRETR KATWFTQVPV SLTRANGSAN
     FGSEWSASIS RAGDYLLYTW LRVRIPSVTL LSTNQFGANG RIRWCRNFMH NLIRECSITF
     NDLVAARFDH YHLDFWAAFT TPASKAVGYD NMIGNVSALI QPQPVPVAPA TVSLPEADLN
     LPLPFFFSRD SGVALPTAAL PYNEMRINFQ FHDWQRLLIL DNIAAVASQT VVPVVGATSD
     IATAPVLHHG TVWGNYAIVS NEERRRMGCS VRDILVEQVQ TAPRHVWNPT TNDAPNYDIR
     FSHAIKALFF AVRNTTFSNQ PSNYTTASPV ITSTTVILEP STGAFDPIHH TTLIYENTNR
     LNHMGSDYFS LVNPWYHAPT IPGLTGFHEY SYSLAFNEID PMGSTNYGKL TNISIVPTAS
     PAAKVGAAGT GPAGSGQNFP QTFEFIVTAL NNNIIRISGG ALGFPVL