MCP_IRV1
ID MCP_IRV1 Reviewed; 464 AA.
AC P18162;
DT 01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1990, sequence version 1.
DT 23-FEB-2022, entry version 73.
DE RecName: Full=Major capsid protein;
DE Short=MCP;
DE AltName: Full=P50;
GN Name=MCP;
OS Tipula iridescent virus (TIV) (Insect iridescent virus type 1).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC Pimascovirales; Iridoviridae; Betairidovirinae; Iridovirus.
OX NCBI_TaxID=10490;
OH NCBI_TaxID=41043; Tipula.
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PARTIAL PROTEIN SEQUENCE.
RX PubMed=2293661; DOI=10.1128/jvi.64.1.125-136.1990;
RA Tajbakhsh S., Lee P.E., Watson D.C., Seligy V.L.;
RT "Molecular cloning, characterization, and expression of the Tipula
RT iridescent virus capsid gene.";
RL J. Virol. 64:125-136(1990).
CC -!- FUNCTION: Major capsid protein that self assembles to form an
CC icosahedral capsid. Represents around 50% of the total virion protein
CC mass (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Homotrimer. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC -!- PTM: The N-terminus is blocked.
CC -!- SIMILARITY: Belongs to the NCLDV major capsid protein family.
CC {ECO:0000305}.
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DR EMBL; M33542; AAA46245.1; -; Genomic_DNA.
DR PIR; A33558; VCXFTI.
DR SMR; P18162; -.
DR GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 2.70.9.20; -; 1.
DR InterPro; IPR031654; Capsid_N.
DR InterPro; IPR007542; MCP_C.
DR InterPro; IPR038519; MCP_C_sf.
DR InterPro; IPR016112; VP_dsDNA_II.
DR Pfam; PF16903; Capsid_N; 1.
DR Pfam; PF04451; Capsid_NCLDV; 1.
DR SUPFAM; SSF49749; SSF49749; 2.
PE 1: Evidence at protein level;
KW Capsid protein; Direct protein sequencing; Late protein; Virion.
FT CHAIN 1..464
FT /note="Major capsid protein"
FT /id="PRO_0000222380"
SQ SEQUENCE 464 AA; 50833 MW; BCDD65F326270910 CRC64;
MSMSSSNITS GFIDIATFDE IEKYMYGGPT ATAYFVREIR KSTWFTQVPV PLSRNTGNAA
FGQEWSVSIS RAGDYLLQTW LRVNIPPVTL SGLLGNTYSL RWTKNLMHNL IREATITFND
LVAARFDNYH LDFWSAFTVP ASKRNGYDNM IGNVSSLINP VAPGGTLGSV GGINLNLPLP
FFFSRDTGVA LPTAALPYNE MQINFNFRDW HELLILTNSA LVPPASPYVP IVVGTHISAA
PVLGPVQVWA NYAIVSNEER RRMGCAIRDI LIEQVQTAPR QNYVPLTNAS PTFDIRFSHA
IKALFFAVRN KTSAAEWSNY ATSSPVVTGA TVNYEPTGSF DPIANTTLIY ENTNRLGAMG
SDYFSLINPF YHAPTIPSFI GYHLYSYSLH FYDLDPMGST NYGKLTNVSV VPQASPAAIA
AAGGTGGQAG SDYPQNYEFV ILAVNNNIVR ISGGETPQNY IAVC