ID   MCRC_METTH              Reviewed;         198 AA.
AC   O27234; Q50491;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Methyl-coenzyme M reductase I operon protein C;
GN   Name=mcrC; OrderedLocusNames=MTH_1166;
OS   Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS   10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=187420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX   PubMed=7929010; DOI=10.1128/jb.176.20.6384-6391.1994;
RA   Pihl T.D., Sharma S., Reeve J.N.;
RT   "Growth phase-dependent transcription of the genes that encode the two
RT   methyl coenzyme M reductase isoenzymes and N5-
RT   methyltetrahydromethanopterin:coenzyme M methyltransferase in
RT   Methanobacterium thermoautotrophicum delta H.";
RL   J. Bacteriol. 176:6384-6391(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX   PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA   Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA   Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA   Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA   Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA   Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA   Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA   Reeve J.N.;
RT   "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT   functional analysis and comparative genomics.";
RL   J. Bacteriol. 179:7135-7155(1997).
CC   -!- SUBUNIT: MCR is composed of three subunits: alpha, beta, and gamma. The
CC       function of proteins C and D is not known.
CC   -!- DEVELOPMENTAL STAGE: There are two MCR complexes in this bacteria. MCR
CC       II is expressed in the early growth phase. Late growth cells contains
CC       mostly MCR I.
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DR   EMBL; U10036; AAA73443.1; -; Genomic_DNA.
DR   EMBL; AE000666; AAB85655.1; -; Genomic_DNA.
DR   PIR; D69022; D69022.
DR   RefSeq; WP_010876790.1; NC_000916.1.
DR   AlphaFoldDB; O27234; -.
DR   SMR; O27234; -.
DR   STRING; 187420.MTH_1166; -.
DR   EnsemblBacteria; AAB85655; AAB85655; MTH_1166.
DR   GeneID; 24854290; -.
DR   KEGG; mth:MTH_1166; -.
DR   PATRIC; fig|187420.15.peg.1143; -.
DR   HOGENOM; CLU_099719_0_0_2; -.
DR   OMA; PVCEITF; -.
DR   Proteomes; UP000005223; Chromosome.
DR   GO; GO:0015948; P:methanogenesis; IEA:UniProtKB-KW.
DR   InterPro; IPR007687; Me_CoM_Rdtase_prot-C.
DR   PIRSF; PIRSF003137; McrC; 1.
DR   TIGRFAMs; TIGR03264; met_CoM_red_C; 1.
PE   2: Evidence at transcript level;
KW   Methanogenesis; Reference proteome.
FT   CHAIN           1..198
FT                   /note="Methyl-coenzyme M reductase I operon protein C"
FT                   /id="PRO_0000147487"
FT   CONFLICT        160
FT                   /note="P -> G (in Ref. 1; AAA73443)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   198 AA;  21221 MW;  991F3AA5C1CE2344 CRC64;
     MIGKCTHVVD CRETMGMGEG GGIAQRGTFA QCGSEVLAVA MSPGRRHITK PVCEITFALR
     EANIMTSTIV LNAGAGVPQD APSAGAGSLF GLTPAEVEQM KRHKLLVVHL GGVKNHITYK
     ARLILRNVDR PCIIICEYPV DFEDFAKIGV RTRAVMPDEP KTKGTIVDIV SGVIRGETCP
     QEKLDEIIRK VKLALGGA