MCRD_METTM
ID MCRD_METTM Reviewed; 145 AA.
AC P11564; D9PY32;
DT 01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT 30-NOV-2010, sequence version 2.
DT 25-MAY-2022, entry version 88.
DE RecName: Full=Methyl-coenzyme M reductase I operon protein D;
GN Name=mcrD; OrderedLocusNames=MTBMA_c15510;
OS Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM
OS 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium
OS thermoautotrophicum).
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX NCBI_TaxID=79929;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 /
RC Marburg;
RX PubMed=2448287; DOI=10.1128/jb.170.2.568-577.1988;
RA Bokranz M., Baeumner G., Allmansberger R., Ankel-Fuchs D., Klein A.;
RT "Cloning and characterization of the methyl coenzyme M reductase genes from
RT Methanobacterium thermoautotrophicum.";
RL J. Bacteriol. 170:568-577(1988).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 /
RC Marburg;
RX PubMed=20802048; DOI=10.1128/jb.00844-10;
RA Liesegang H., Kaster A.K., Wiezer A., Goenrich M., Wollherr A., Seedorf H.,
RA Gottschalk G., Thauer R.K.;
RT "Complete genome sequence of Methanothermobacter marburgensis, a
RT methanoarchaeon model organism.";
RL J. Bacteriol. 192:5850-5851(2010).
CC -!- SUBUNIT: MCR is composed of three subunits: alpha, beta, and gamma. The
CC function of proteins C and D is not known.
CC -!- DEVELOPMENTAL STAGE: There are two MCR complexes in this bacteria. MCR
CC II is expressed in the early growth phase. Late growth cells contains
CC mostly MCR I.
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DR EMBL; X07794; CAA30636.1; -; Genomic_DNA.
DR EMBL; CP001710; ADL59130.1; -; Genomic_DNA.
DR RefSeq; WP_013296340.1; NC_014408.1.
DR AlphaFoldDB; P11564; -.
DR STRING; 79929.MTBMA_c15510; -.
DR EnsemblBacteria; ADL59130; ADL59130; MTBMA_c15510.
DR GeneID; 9705260; -.
DR KEGG; mmg:MTBMA_c15510; -.
DR PATRIC; fig|79929.8.peg.1504; -.
DR HOGENOM; CLU_118415_0_0_2; -.
DR OMA; GIRRMMI; -.
DR OrthoDB; 94905at2157; -.
DR Proteomes; UP000000345; Chromosome.
DR GO; GO:0015948; P:methanogenesis; IEA:UniProtKB-KW.
DR InterPro; IPR003901; Me_CoM_Rdtase_D.
DR Pfam; PF02505; MCR_D; 1.
DR PIRSF; PIRSF005636; McrD; 1.
DR TIGRFAMs; TIGR03260; met_CoM_red_D; 1.
PE 2: Evidence at transcript level;
KW Methanogenesis.
FT CHAIN 1..145
FT /note="Methyl-coenzyme M reductase I operon protein D"
FT /id="PRO_0000147497"
FT CONFLICT 116..145
FT /note="DEIPDELIGLTDQNARLSERATIIKRKKEH -> MRFLMNSSVSRIRTPGSV
FT KGPQ (in Ref. 1; CAA30636)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 145 AA; 16811 MW; 04F950E08E712F6F CRC64;
MDVQIFPHRL LGADTTEKLL NRLEDIHGVK RMVIHGQRLP PEDHPDRRII NVKGQEFELQ
VKTGRVLLEV EDEETITDIK RVCEDLLPFG YDVTPGKYIR TEKTVTDEIK YGESLDEIPD
ELIGLTDQNA RLSERATIIK RKKEH