MCRI1_CHICK
ID MCRI1_CHICK Reviewed; 96 AA.
AC Q5ZIU1;
DT 18-MAY-2010, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 51.
DE RecName: Full=Mapk-regulated corepressor-interacting protein 1;
DE AltName: Full=Protein FAM195B;
GN Name=MCRIP1; Synonyms=FAM195B; ORFNames=RCJMB04_23i24;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=CB; TISSUE=Bursa of Fabricius;
RX PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA Hayashizaki Y., Buerstedde J.-M.;
RT "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT function analysis.";
RL Genome Biol. 6:R6.1-R6.9(2005).
CC -!- FUNCTION: May play a role in the regulation of the epithelial-
CC mesenchymal transition. {ECO:0000250|UniProtKB:C9JLW8}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:C9JLW8}.
CC Cytoplasm, Stress granule {ECO:0000250|UniProtKB:C9JLW8}.
CC -!- SIMILARITY: Belongs to the MCRIP family. {ECO:0000305}.
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DR EMBL; AJ720693; CAG32352.1; -; mRNA.
DR RefSeq; NP_001292004.1; NM_001305075.1.
DR RefSeq; NP_001292005.1; NM_001305076.1.
DR RefSeq; XP_015150856.1; XM_015295370.1.
DR RefSeq; XP_015150857.1; XM_015295371.1.
DR RefSeq; XP_015150858.1; XM_015295372.1.
DR AlphaFoldDB; Q5ZIU1; -.
DR Ensembl; ENSGALT00000074826; ENSGALP00000057973; ENSGALG00000042814.
DR Ensembl; ENSGALT00000080751; ENSGALP00000044582; ENSGALG00000042814.
DR GeneID; 101749776; -.
DR KEGG; gga:101749776; -.
DR CTD; 348262; -.
DR VEuPathDB; HostDB:geneid_101749776; -.
DR GeneTree; ENSGT00940000161850; -.
DR InParanoid; Q5ZIU1; -.
DR OrthoDB; 1461250at2759; -.
DR PhylomeDB; Q5ZIU1; -.
DR PRO; PR:Q5ZIU1; -.
DR Proteomes; UP000000539; Chromosome 18.
DR Bgee; ENSGALG00000042814; Expressed in spermatid and 13 other tissues.
DR ExpressionAtlas; Q5ZIU1; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR GO; GO:0010494; C:cytoplasmic stress granule; ISS:UniProtKB.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0010717; P:regulation of epithelial to mesenchymal transition; ISS:UniProtKB.
DR InterPro; IPR029428; MCRIP.
DR Pfam; PF14799; FAM195; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Nucleus; Reference proteome.
FT CHAIN 1..96
FT /note="Mapk-regulated corepressor-interacting protein 1"
FT /id="PRO_0000393957"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 76..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 79..83
FT /note="PXDLS motif"
FT /evidence="ECO:0000305"
FT COMPBIAS 80..96
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 96 AA; 10786 MW; E57ADD00418788CC CRC64;
MASSPVSRVV YNGKRSGGPR SPGAGSEIFT PAHEENVRFI YEAWQCVERD LRSQMGSERG
LVEEYVEKMP NPSLKAFKPV DLSDLKRRNT QDAKKS