ID   MCRI1_DANRE             Reviewed;          97 AA.
AC   Q0P4B9;
DT   18-MAY-2010, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Mapk-regulated corepressor-interacting protein 1;
DE   AltName: Full=Protein FAM195B;
GN   Name=mcrip1; Synonyms=fam195b; ORFNames=zgc:153165;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Olfactory epithelium;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS], AND IDENTIFICATION BY MASS
RP   SPECTROMETRY.
RC   TISSUE=Embryo;
RX   PubMed=18307296; DOI=10.1021/pr700667w;
RA   Lemeer S., Pinkse M.W.H., Mohammed S., van Breukelen B., den Hertog J.,
RA   Slijper M., Heck A.J.R.;
RT   "Online automated in vivo zebrafish phosphoproteomics: from large-scale
RT   analysis down to a single embryo.";
RL   J. Proteome Res. 7:1555-1564(2008).
CC   -!- FUNCTION: May play a role in the regulation of the epithelial-
CC       mesenchymal transition. {ECO:0000250|UniProtKB:C9JLW8}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:C9JLW8}.
CC       Cytoplasm, Stress granule {ECO:0000250|UniProtKB:C9JLW8}.
CC   -!- SIMILARITY: Belongs to the MCRIP family. {ECO:0000305}.
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DR   EMBL; BC122169; AAI22170.1; -; mRNA.
DR   RefSeq; NP_001038936.1; NM_001045471.2.
DR   AlphaFoldDB; Q0P4B9; -.
DR   STRING; 7955.ENSDARP00000092790; -.
DR   PaxDb; Q0P4B9; -.
DR   PRIDE; Q0P4B9; -.
DR   Ensembl; ENSDART00000102014; ENSDARP00000092790; ENSDARG00000078383.
DR   GeneID; 751762; -.
DR   KEGG; dre:751762; -.
DR   CTD; 348262; -.
DR   ZFIN; ZDB-GENE-060825-259; mcrip1.
DR   eggNOG; ENOG502S25D; Eukaryota.
DR   GeneTree; ENSGT00940000161850; -.
DR   HOGENOM; CLU_161057_0_0_1; -.
DR   InParanoid; Q0P4B9; -.
DR   OMA; QNHERND; -.
DR   OrthoDB; 1461250at2759; -.
DR   PhylomeDB; Q0P4B9; -.
DR   TreeFam; TF326620; -.
DR   PRO; PR:Q0P4B9; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 3.
DR   Bgee; ENSDARG00000078383; Expressed in mature ovarian follicle and 26 other tissues.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0010494; C:cytoplasmic stress granule; ISS:UniProtKB.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0010717; P:regulation of epithelial to mesenchymal transition; ISS:UniProtKB.
DR   InterPro; IPR029428; MCRIP.
DR   Pfam; PF14799; FAM195; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..97
FT                   /note="Mapk-regulated corepressor-interacting protein 1"
FT                   /id="PRO_0000393959"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          54..97
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           80..84
FT                   /note="PXDLS motif"
FT                   /evidence="ECO:0000305"
FT   COMPBIAS        82..97
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   97 AA;  11291 MW;  FD734E0BC01B2C09 CRC64;
     MTSSSTPRMH TYKRTSSPRS PTNTGELFTP AHEENVRFIH DTWLCVLRDI KCPQNHERND
     RGPQEYVEKN PNPNLHSFIP VDLSDLKKRN TQDSKKS