MCRW_METTH
ID MCRW_METTH Reviewed; 162 AA.
AC Q50485; O27203;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2000, sequence version 2.
DT 25-MAY-2022, entry version 103.
DE RecName: Full=Methyl-coenzyme M reductase II operon protein D;
GN Name=mrtD; OrderedLocusNames=MTH_1131;
OS Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX NCBI_TaxID=187420;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX PubMed=7929010; DOI=10.1128/jb.176.20.6384-6391.1994;
RA Pihl T.D., Sharma S., Reeve J.N.;
RT "Growth phase-dependent transcription of the genes that encode the two
RT methyl coenzyme M reductase isoenzymes and N5-
RT methyltetrahydromethanopterin:coenzyme M methyltransferase in
RT Methanobacterium thermoautotrophicum delta H.";
RL J. Bacteriol. 176:6384-6391(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA Reeve J.N.;
RT "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT functional analysis and comparative genomics.";
RL J. Bacteriol. 179:7135-7155(1997).
CC -!- SUBUNIT: MCR is composed of three subunits: alpha, beta, and gamma. The
CC function of protein D is not known.
CC -!- DEVELOPMENTAL STAGE: There are two MCR complexes in this bacteria. MCR
CC II is expressed in the early growth phase. Late growth cells contains
CC mostly MCR I.
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DR EMBL; U09990; AAA73437.1; -; Genomic_DNA.
DR EMBL; AE000666; AAB85620.1; -; Genomic_DNA.
DR PIR; F69017; F69017.
DR PIR; T45148; T45148.
DR RefSeq; WP_010876755.1; NC_000916.1.
DR AlphaFoldDB; Q50485; -.
DR STRING; 187420.MTH_1131; -.
DR DNASU; 1471539; -.
DR EnsemblBacteria; AAB85620; AAB85620; MTH_1131.
DR GeneID; 1471539; -.
DR KEGG; mth:MTH_1131; -.
DR PATRIC; fig|187420.15.peg.1108; -.
DR HOGENOM; CLU_118415_0_0_2; -.
DR OMA; NFPYGYD; -.
DR Proteomes; UP000005223; Chromosome.
DR GO; GO:0015948; P:methanogenesis; IEA:UniProtKB-KW.
DR InterPro; IPR003901; Me_CoM_Rdtase_D.
DR Pfam; PF02505; MCR_D; 1.
DR PIRSF; PIRSF005636; McrD; 1.
DR TIGRFAMs; TIGR03260; met_CoM_red_D; 1.
PE 2: Evidence at transcript level;
KW Methanogenesis; Reference proteome.
FT CHAIN 1..162
FT /note="Methyl-coenzyme M reductase II operon protein D"
FT /id="PRO_0000147498"
FT CONFLICT 44..52
FT /note="PSIPDRVYY -> HQYPTVTT (in Ref. 1; AAA73437)"
FT /evidence="ECO:0000305"
FT CONFLICT 58..59
FT /note="TE -> QR (in Ref. 1; AAA73437)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 162 AA; 18619 MW; 3D90667C7BB1D164 CRC64;
MMSETGFIDV KIFPQRLLKP ETAEKLLNRI YELEGIVRVL VHGPSIPDRV YYGPARGTEV
NHSDRRKITV RGEEFELRVK VGEIIVGMLP ETLEEKMETI EEILDEVLPC SYKVFIGAFT
KKDITISDYL KYGLKFEEKI DPRVIGMVDP SSRMKDTVVN IK
