ID   MCS1A_XENLA             Reviewed;         181 AA.
AC   Q5PPY1;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Malignant T-cell-amplified sequence 1-A;
DE            Short=MCT-1A;
GN   Name=mcts1-a;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role as translation enhancer and involved in cell
CC       cycle regulation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- DOMAIN: The PUA RNA-binding domain is critical for cap binding, but not
CC       sufficient for translation enhancer function. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MCTS1 family. {ECO:0000305}.
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DR   EMBL; BC087444; AAH87444.1; -; mRNA.
DR   EMBL; BC106233; AAI06234.1; -; mRNA.
DR   RefSeq; NP_001089037.1; NM_001095568.1.
DR   AlphaFoldDB; Q5PPY1; -.
DR   SMR; Q5PPY1; -.
DR   BioGRID; 106503; 1.
DR   IntAct; Q5PPY1; 1.
DR   DNASU; 503679; -.
DR   GeneID; 503679; -.
DR   KEGG; xla:503679; -.
DR   CTD; 503679; -.
DR   Xenbase; XB-GENE-998587; mcts1.S.
DR   OMA; HDHIEIL; -.
DR   OrthoDB; 1257440at2759; -.
DR   Proteomes; UP000186698; Chromosome 8S.
DR   Bgee; 503679; Expressed in oocyte and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   InterPro; IPR016437; MCT-1/Tma20.
DR   InterPro; IPR041366; Pre-PUA.
DR   InterPro; IPR002478; PUA.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR004521; Uncharacterised_CHP00451.
DR   PANTHER; PTHR22798; PTHR22798; 1.
DR   Pfam; PF17832; Pre-PUA; 1.
DR   Pfam; PF01472; PUA; 1.
DR   PIRSF; PIRSF005067; Tma_RNA-bind_prd; 1.
DR   SMART; SM00359; PUA; 1.
DR   SUPFAM; SSF88697; SSF88697; 1.
DR   TIGRFAMs; TIGR00451; unchar_dom_2; 1.
DR   PROSITE; PS50890; PUA; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cytoplasm; Growth regulation; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..181
FT                   /note="Malignant T-cell-amplified sequence 1-A"
FT                   /id="PRO_0000344792"
FT   DOMAIN          92..171
FT                   /note="PUA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00161"
SQ   SEQUENCE   181 AA;  20530 MW;  58F8D101F49712F0 CRC64;
     MFKKFDEKEN VSNCIQLKTS VIKGIKNQLI DQFPGIEQWL NQIMPKKDPV KIVRCHEHIE
     ILTVNGELLF FRQREGPFYP TLRLLHKYPF ILPHQQVDKG AIKFVLSGAN IMCPGLTSPG
     AKLYPAAADT VVAIMAEGKQ HALCVGVMKM SADDIEKINK GIGIENIHYL NDGLWHMKTY
     K