ID   MCTR_RHIL3              Reviewed;         214 AA.
AC   Q1M7A0; Q8RJZ9;
DT   29-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2006, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Transcriptional regulatory protein MctR {ECO:0000305};
GN   Name=mctR {ECO:0000303|PubMed:12218032};
GN   OrderedLocusNames=pRL100406 {ECO:0000312|EMBL:CAK10632.1};
OS   Rhizobium leguminosarum bv. viciae (strain 3841).
OG   Plasmid pRL10 {ECO:0000312|EMBL:CAK10632.1}.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=216596;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC   STRAIN=3841;
RX   PubMed=12218032; DOI=10.1128/jb.184.19.5436-5448.2002;
RA   Hosie A.H., Allaway D., Poole P.S.;
RT   "A monocarboxylate permease of Rhizobium leguminosarum is the first member
RT   of a new subfamily of transporters.";
RL   J. Bacteriol. 184:5436-5448(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=3841;
RX   PubMed=16640791; DOI=10.1186/gb-2006-7-4-r34;
RA   Young J.P.W., Crossman L.C., Johnston A.W.B., Thomson N.R., Ghazoui Z.F.,
RA   Hull K.H., Wexler M., Curson A.R.J., Todd J.D., Poole P.S., Mauchline T.H.,
RA   East A.K., Quail M.A., Churcher C., Arrowsmith C., Cherevach I.,
RA   Chillingworth T., Clarke K., Cronin A., Davis P., Fraser A., Hance Z.,
RA   Hauser H., Jagels K., Moule S., Mungall K., Norbertczak H.,
RA   Rabbinowitsch E., Sanders M., Simmonds M., Whitehead S., Parkhill J.;
RT   "The genome of Rhizobium leguminosarum has recognizable core and accessory
RT   components.";
RL   Genome Biol. 7:R34.1-R34.20(2006).
CC   -!- FUNCTION: Member of the two-component regulatory system MctS/MctR,
CC       which activates mctP expression. {ECO:0000269|PubMed:12218032}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
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DR   EMBL; AJ421944; CAD19127.2; -; Genomic_DNA.
DR   EMBL; AM236084; CAK10632.1; -; Genomic_DNA.
DR   RefSeq; WP_011654430.1; NC_008381.1.
DR   AlphaFoldDB; Q1M7A0; -.
DR   SMR; Q1M7A0; -.
DR   EnsemblBacteria; CAK10632; CAK10632; pRL100406.
DR   KEGG; rle:pRL100406; -.
DR   HOGENOM; CLU_000445_90_1_5; -.
DR   OMA; HPMWRDG; -.
DR   OrthoDB; 1687028at2; -.
DR   Proteomes; UP000006575; Plasmid pRL10.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   Pfam; PF00196; GerE; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   3: Inferred from homology;
KW   Activator; Cytoplasm; DNA-binding; Phosphoprotein; Plasmid; Transcription;
KW   Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..214
FT                   /note="Transcriptional regulatory protein MctR"
FT                   /id="PRO_0000430567"
FT   DOMAIN          8..124
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DOMAIN          143..208
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT   DNA_BIND        167..186
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT   MOD_RES         59
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   214 AA;  23060 MW;  0159B7DEE0221DFD CRC64;
     MTERPKIRVL LIDNHPLVLD GLKAVLETFD HIEVAGTAGL AQTGLEIGRQ ILPQVVLMDI
     NMPKLSGIDA IELFRNELPQ ARVVMLSMHD SREYISSSVM HGAAGYILKD VSTDEIVSAI
     ETVAGGGTYF SSGVFDALMG ERVEEGSDPL TPRERDILGL IVAGRSNKEI AETLGITSAT
     AETHRKNLKK KLGITTTAGL IRYALDHGIV SKVG