ID   MCTS1_DANRE             Reviewed;         181 AA.
AC   Q7ZV34;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Malignant T-cell-amplified sequence 1;
DE            Short=MCT-1;
GN   Name=mcts1; ORFNames=zgc:56242;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role as translation enhancer and involved in cell
CC       cycle regulation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- DOMAIN: The PUA RNA-binding domain is critical for cap binding, but not
CC       sufficient for translation enhancer function. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MCTS1 family. {ECO:0000305}.
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DR   EMBL; BC046019; AAH46019.1; -; mRNA.
DR   RefSeq; NP_957365.1; NM_201071.1.
DR   AlphaFoldDB; Q7ZV34; -.
DR   SMR; Q7ZV34; -.
DR   STRING; 7955.ENSDARP00000037227; -.
DR   PaxDb; Q7ZV34; -.
DR   GeneID; 394046; -.
DR   KEGG; dre:394046; -.
DR   CTD; 28985; -.
DR   ZFIN; ZDB-GENE-040426-957; mcts1.
DR   eggNOG; KOG2523; Eukaryota.
DR   InParanoid; Q7ZV34; -.
DR   OrthoDB; 1257440at2759; -.
DR   PhylomeDB; Q7ZV34; -.
DR   PRO; PR:Q7ZV34; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IBA:GO_Central.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   InterPro; IPR016437; MCT-1/Tma20.
DR   InterPro; IPR041366; Pre-PUA.
DR   InterPro; IPR002478; PUA.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR004521; Uncharacterised_CHP00451.
DR   PANTHER; PTHR22798; PTHR22798; 1.
DR   Pfam; PF17832; Pre-PUA; 1.
DR   Pfam; PF01472; PUA; 1.
DR   PIRSF; PIRSF005067; Tma_RNA-bind_prd; 1.
DR   SMART; SM00359; PUA; 1.
DR   SUPFAM; SSF88697; SSF88697; 1.
DR   TIGRFAMs; TIGR00451; unchar_dom_2; 1.
DR   PROSITE; PS50890; PUA; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cytoplasm; Growth regulation; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..181
FT                   /note="Malignant T-cell-amplified sequence 1"
FT                   /id="PRO_0000344791"
FT   DOMAIN          92..171
FT                   /note="PUA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00161"
SQ   SEQUENCE   181 AA;  20609 MW;  84940BAFE2929648 CRC64;
     MFKKFDEKEN VSNCIQLKTS VIKGIKNQLL DQFPNIDDWL NQIMPKKDPV KIVRCHEHIE
     ILTVNGELLF FRQREGPFYP TLRLLHKYPF ILPHQQVDKG AIKFVLSGAN IMCPGLTSPG
     AKLYPAESDT VVAIMAEGKQ HALCVGVMKM SADDIEKVNM GIGIENVHYL NDGLWHMKTY
     K