MDA3_ARATH
ID MDA3_ARATH Reviewed; 92 AA.
AC Q9FHX8;
DT 03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Mediator-associated protein 3;
DE AltName: Full=DEK-domain containing protein At5g42060;
DE AltName: Full=KELP-like protein;
GN OrderedLocusNames=At5g42060; ORFNames=MJC20.17;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10470850; DOI=10.1093/dnares/6.3.183;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Kotani H.,
RA Miyajima N., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IX. Sequence
RT features of the regions of 1,011,550 bp covered by seventeen P1 and TAC
RT clones.";
RL DNA Res. 6:183-195(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND SUBUNIT.
RX PubMed=17560376; DOI=10.1016/j.molcel.2007.05.007;
RA Baeckstroem S., Elfving N., Nilsson R., Wingsle G., Bjoerklund S.;
RT "Purification of a plant mediator from Arabidopsis thaliana identifies PFT1
RT as the Med25 subunit.";
RL Mol. Cell 26:717-729(2007).
CC -!- SUBUNIT: Associated with the Mediator complex.
CC {ECO:0000269|PubMed:17560376}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR EMBL; AB017067; BAB08439.1; -; Genomic_DNA.
DR EMBL; CP002688; AED94761.1; -; Genomic_DNA.
DR EMBL; AY072311; AAL61918.1; -; mRNA.
DR EMBL; AY114547; AAM47866.1; -; mRNA.
DR RefSeq; NP_199021.1; NM_123571.3.
DR AlphaFoldDB; Q9FHX8; -.
DR SMR; Q9FHX8; -.
DR BioGRID; 19461; 1.
DR IntAct; Q9FHX8; 2.
DR STRING; 3702.AT5G42060.1; -.
DR PaxDb; Q9FHX8; -.
DR PRIDE; Q9FHX8; -.
DR ProteomicsDB; 238825; -.
DR DNASU; 834211; -.
DR EnsemblPlants; AT5G42060.1; AT5G42060.1; AT5G42060.
DR GeneID; 834211; -.
DR Gramene; AT5G42060.1; AT5G42060.1; AT5G42060.
DR KEGG; ath:AT5G42060; -.
DR Araport; AT5G42060; -.
DR TAIR; locus:2165780; AT5G42060.
DR HOGENOM; CLU_2416307_0_0_1; -.
DR InParanoid; Q9FHX8; -.
DR OMA; AMLPKRI; -.
DR OrthoDB; 1625566at2759; -.
DR PhylomeDB; Q9FHX8; -.
DR PRO; PR:Q9FHX8; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FHX8; baseline and differential.
DR Genevisible; Q9FHX8; AT.
DR GO; GO:0016592; C:mediator complex; IDA:UniProtKB.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005667; C:transcription regulator complex; IBA:GO_Central.
DR GO; GO:0003713; F:transcription coactivator activity; IBA:GO_Central.
DR GO; GO:0060261; P:positive regulation of transcription initiation from RNA polymerase II promoter; IBA:GO_Central.
DR InterPro; IPR014876; DEK_C.
DR InterPro; IPR045125; Sub1/Tcp4-like.
DR PANTHER; PTHR13215; PTHR13215; 1.
DR Pfam; PF08766; DEK_C; 1.
DR PROSITE; PS51998; DEK_C; 1.
PE 1: Evidence at protein level;
KW Nucleus; Reference proteome.
FT CHAIN 1..92
FT /note="Mediator-associated protein 3"
FT /id="PRO_0000419195"
FT DOMAIN 13..70
FT /note="DEK-C"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01342"
SQ SEQUENCE 92 AA; 10702 MW; 217732172809BE69 CRC64;
MEEVAREEVE IDKDLRRKIK KTVKKILESS NLYKITEIKA REEASLKLDL DLSQDPYKVI
VKEEVENFLE EAVKLIGNKL AMLPKRIEST SI