MDCG_XANC8
ID MDCG_XANC8 Reviewed; 213 AA.
AC Q4UZ66;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2005, sequence version 1.
DT 25-MAY-2022, entry version 72.
DE RecName: Full=Phosphoribosyl-dephospho-CoA transferase {ECO:0000255|HAMAP-Rule:MF_00650};
DE EC=2.7.7.66 {ECO:0000255|HAMAP-Rule:MF_00650};
DE AltName: Full=Malonate decarboxylase holo-[acyl-carrier-protein] synthase {ECO:0000255|HAMAP-Rule:MF_00650};
DE Short=Holo-ACP synthase {ECO:0000255|HAMAP-Rule:MF_00650};
GN Name=mdcG {ECO:0000255|HAMAP-Rule:MF_00650}; OrderedLocusNames=XC_0576;
OS Xanthomonas campestris pv. campestris (strain 8004).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Xanthomonas.
OX NCBI_TaxID=314565;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=8004;
RX PubMed=15899963; DOI=10.1101/gr.3378705;
RA Qian W., Jia Y., Ren S.-X., He Y.-Q., Feng J.-X., Lu L.-F., Sun Q.,
RA Ying G., Tang D.-J., Tang H., Wu W., Hao P., Wang L., Jiang B.-L., Zeng S.,
RA Gu W.-Y., Lu G., Rong L., Tian Y., Yao Z., Fu G., Chen B., Fang R.,
RA Qiang B., Chen Z., Zhao G.-P., Tang J.-L., He C.;
RT "Comparative and functional genomic analyses of the pathogenicity of
RT phytopathogen Xanthomonas campestris pv. campestris.";
RL Genome Res. 15:757-767(2005).
CC -!- FUNCTION: Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme-A to
CC the apo-[acyl-carrier-protein] of the malonate decarboxylase to yield
CC holo-[acyl-carrier-protein]. {ECO:0000255|HAMAP-Rule:MF_00650}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2'-(5''-triphospho-alpha-D-ribosyl)-3'-dephospho-CoA + apo-
CC [malonate decarboxylase ACP] = diphosphate + holo-[malonate
CC decarboxylase ACP]; Xref=Rhea:RHEA:42644, Rhea:RHEA-COMP:10160,
CC Rhea:RHEA-COMP:10161, ChEBI:CHEBI:29999, ChEBI:CHEBI:33019,
CC ChEBI:CHEBI:61378, ChEBI:CHEBI:82683; EC=2.7.7.66;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00650};
CC -!- SIMILARITY: Belongs to the MdcG family. {ECO:0000255|HAMAP-
CC Rule:MF_00650}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000050; AAY47657.1; -; Genomic_DNA.
DR RefSeq; WP_011038697.1; NC_007086.1.
DR AlphaFoldDB; Q4UZ66; -.
DR EnsemblBacteria; AAY47657; AAY47657; XC_0576.
DR KEGG; xcb:XC_0576; -.
DR HOGENOM; CLU_075747_0_1_6; -.
DR OMA; GGVNWRE; -.
DR OrthoDB; 1407518at2; -.
DR Proteomes; UP000000420; Chromosome.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00650; Malonate_MdcG; 1.
DR InterPro; IPR017557; Holo-ACP_synthase.
DR Pfam; PF10620; MdcG; 1.
DR TIGRFAMs; TIGR03135; malonate_mdcG; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase; Transferase.
FT CHAIN 1..213
FT /note="Phosphoribosyl-dephospho-CoA transferase"
FT /id="PRO_1000061475"
FT ACT_SITE 135
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00650"
FT ACT_SITE 137
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00650"
SQ SEQUENCE 213 AA; 22901 MW; C784E3CD7B061AEF CRC64;
MAGRHALVWL RADAPSQALT PGAQPRLQAW FAAGFPAVVA RRDGAEQPGQ VRLGVPLPPA
QGKQRIALCA QVSDIARSVP ALALPEVISH APPQWQAALH ALQAQATAIG MQPRVFGSFA
FQAVTGLPYV HAASDVDLLW TLDTPTQAHA VVTLLQQWEH VTARRADGEL LLPDGNAVNW
REYAGDAQQV LVKRNDGCRL LPRTALFPER CAA