ID   MDE6_SCHPO              Reviewed;         700 AA.
AC   O13730;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   22-SEP-2009, sequence version 2.
DT   25-MAY-2022, entry version 122.
DE   RecName: Full=Mei4-dependent protein 6;
GN   Name=mde6; ORFNames=SPAC15A10.10;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- MISCELLANEOUS: Transcription is induced by mei4 transcription factor.
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DR   EMBL; CU329670; CAB10107.2; -; Genomic_DNA.
DR   PIR; T37710; T37710.
DR   RefSeq; NP_594297.2; NM_001019720.3.
DR   AlphaFoldDB; O13730; -.
DR   SMR; O13730; -.
DR   BioGRID; 279219; 12.
DR   STRING; 4896.SPAC15A10.10.1; -.
DR   PaxDb; O13730; -.
DR   PRIDE; O13730; -.
DR   EnsemblFungi; SPAC15A10.10.1; SPAC15A10.10.1:pep; SPAC15A10.10.
DR   GeneID; 2542769; -.
DR   KEGG; spo:SPAC15A10.10; -.
DR   PomBase; SPAC15A10.10; mde6.
DR   VEuPathDB; FungiDB:SPAC15A10.10; -.
DR   eggNOG; KOG2437; Eukaryota.
DR   HOGENOM; CLU_004210_1_0_1; -.
DR   InParanoid; O13730; -.
DR   OMA; MGHCMEY; -.
DR   PhylomeDB; O13730; -.
DR   PRO; PR:O13730; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR   Gene3D; 2.120.10.80; -; 2.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR011498; Kelch_2.
DR   InterPro; IPR010565; Muskelin_N.
DR   Pfam; PF07646; Kelch_2; 1.
DR   Pfam; PF06588; Muskelin_N; 1.
DR   SUPFAM; SSF117281; SSF117281; 1.
DR   SUPFAM; SSF49785; SSF49785; 1.
PE   4: Predicted;
KW   Kelch repeat; Reference proteome; Repeat.
FT   CHAIN           1..700
FT                   /note="Mei4-dependent protein 6"
FT                   /id="PRO_0000119148"
FT   REPEAT          276..322
FT                   /note="Kelch 1"
FT   REPEAT          327..381
FT                   /note="Kelch 2"
FT   REPEAT          390..439
FT                   /note="Kelch 3"
FT   REPEAT          452..499
FT                   /note="Kelch 4"
FT   REPEAT          508..558
FT                   /note="Kelch 5"
FT   REPEAT          569..619
FT                   /note="Kelch 6"
SQ   SEQUENCE   700 AA;  81659 MW;  1CC64859932AE374 CRC64;
     MERKELSYTI QSWSSYSGAF HPINILIDNP HQANSRWSCN TSICKPNNSE EQYVILKLDK
     LALVTDITFG KFHTPHLCNL KDFIVYGGRE QHLMFPLLRA GLTNDSNRET FPLCIKKYNK
     IENSIACKYI KIVPLQAHAH EFNMSIWYVA LHGIDSASAL SCTEKNRALH LEKKALNCLL
     SYFAFKGKLD ICSVILQSYQ LSIPHSPLMR MYDAFCRLGD TQKTILLFQQ ELQAEIIEKW
     PKHKLTKLRS HRIATFLKGI SRRSGHQMVY NPKDNCIYLY GGWDGVKTFS DFWIYNVDKD
     LWIMENEYGI PGERVCHRMV IDTSQQKLYL LGNYFGSSRE TEVPPDARTD FWEFDISKKV
     WTCLSYDTSK DGGPAAIFDH GMSVDEKRGI VYVSGGCKWD PDELVFEGLY AYDTKNRIWE
     QLAVRYEDRQ KHCEFKIERM GHCMEYFPDE NKLYIFGGQS YDQEFILDMC YIKLETREAV
     QHVRKNDTSQ SPSPSFCQRS IMDSKNHRIF TMFGFEQRNI HKVLRPSLWI FYITTEEWVK
     ISDINEEEGN EHPCSRFGHA VAADLNRNII YLMGGNASTH PLRPMKLSDF WKLDILDRWG
     IKHCLSNVSL QLHLHRFHEL VSENLAKAVE YLQKSMQPQF DKSPLFWNAL ILDAFSGTHK
     NKDIAQRRFE TFQTIYDLLP VDENTVAPNE SLLNMIEFFT