MDE7_SCHPO
ID MDE7_SCHPO Reviewed; 761 AA.
AC O59784;
DT 13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 25-MAY-2022, entry version 113.
DE RecName: Full=RNA-binding protein mde7;
DE AltName: Full=Mei4-dependent protein 7;
GN Name=mde7; ORFNames=SPCC320.07c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- MISCELLANEOUS: Transcription is induced by mei4 transcription factor.
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DR EMBL; CU329672; CAA18309.1; -; Genomic_DNA.
DR PIR; T41304; T41304.
DR RefSeq; NP_587722.1; NM_001022717.1.
DR AlphaFoldDB; O59784; -.
DR SMR; O59784; -.
DR BioGRID; 275288; 10.
DR STRING; 4896.SPCC320.07c.1; -.
DR PaxDb; O59784; -.
DR EnsemblFungi; SPCC320.07c.1; SPCC320.07c.1:pep; SPCC320.07c.
DR GeneID; 2538704; -.
DR KEGG; spo:SPCC320.07c; -.
DR PomBase; SPCC320.07c; mde7.
DR VEuPathDB; FungiDB:SPCC320.07c; -.
DR eggNOG; KOG0118; Eukaryota.
DR HOGENOM; CLU_373451_0_0_1; -.
DR InParanoid; O59784; -.
DR OMA; FDIFEIN; -.
DR PRO; PR:O59784; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0061013; P:regulation of mRNA catabolic process; ISO:PomBase.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; SSF54928; 2.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW mRNA processing; mRNA splicing; Reference proteome; Repeat; RNA-binding.
FT CHAIN 1..761
FT /note="RNA-binding protein mde7"
FT /id="PRO_0000081625"
FT DOMAIN 223..289
FT /note="RRM 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT DOMAIN 602..679
FT /note="RRM 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT REGION 31..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 188..213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 442..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..87
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..110
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..213
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..464
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 761 AA; 84301 MW; D08A77FFB46F774F CRC64;
MSQLYALNGQ PLAGKSDDLA NKLAAFGLSQ PNHSSLSEQQ STNSLLHGSG AFNKPPLSRN
STTNPLNLLY TQTQQPARST TPFLLNPVGS SPGKLPVPSR NNSYLQGTAE SNSGNFANNS
ISNNCWNSAY NSNSFEGTGS SPNFPPQNQF LSDSRSSIAT LNAIPSLDQS VLLNPNLRAR
TPSLVPEHYF DDTDKSVHSK SSSGSNSLSE ASNDDLESSI IQIVGGLPDD FDDRELSGIF
TFCEGYDFSK IESENGHRKA IVYFRNAIAA LKAKNMLNAS STNNFTIIQR DVVRQQENEY
HKGIPPLTTP SLYSQRLSNN YDSTTPGFPR FSPANFDSVI NKDVTSESRM STSYPAVLEA
FKSFNPIKAP KAEYLNQSRA SMGNPSPSNW NNRLLQPSSK EQAVYSFQTQ KNSKGLQFTS
NELTNPTAKY SQLPNNIANI GESNSLSNQP NNFAQTSFDY QPNHPNAISP KAKFSLPSRP
SYHKDNSFIS KQAIDKSNPF EEALRLERTS PVKELPAIRP RTIPLNGVAP YESELRPPPK
WKPMPDLKVV RSRPSLKQRP LRSAEYVRVC ELKCLQEEEF DNKVLLEQVE SNVQTDHNSP
CNTIYVGNLS NPDQEKKLRL AFSKEKGYRR LCFKIKGNSP MCFVEFEEVC HAAKAMEKMQ
GAALDDKIKG GIRLSYSKNP LGVRSTENLS TTASLFQQHG PPKKSTDCYS AKASAAVERK
YHFQNMTPKP NGTNSVTTLN RTQTHSSEVN DLFDIFEFPS K
