ID   ARGR_CORGL              Reviewed;         171 AA.
AC   O85175; Q9R988;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   14-AUG-2001, sequence version 2.
DT   03-AUG-2022, entry version 142.
DE   RecName: Full=Arginine repressor;
GN   Name=argR; OrderedLocusNames=Cgl1399, cg1585;
OS   Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 /
OS   JCM 1318 / LMG 3730 / NCIMB 10025).
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=196627;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 13059 / LMG 3658 / NCIB 10332 / AS019 / 613;
RA   Park M.Y., Chun J.Y., Ko S.-Y., Lee M.-S.;
RT   "Molecular cloning of the arginine biosynthetic genes from Corynebacterium
RT   glutamicum.";
RL   Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 13059 / LMG 3658 / NCIB 10332 / AS019 / 613;
RA   Ko S.-Y., Lee M.-S.;
RT   "The argR gene of Corynebacterium glutamicum.";
RL   Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB
RC   10025;
RX   PubMed=12743753; DOI=10.1007/s00253-003-1328-1;
RA   Ikeda M., Nakagawa S.;
RT   "The Corynebacterium glutamicum genome: features and impacts on
RT   biotechnological processes.";
RL   Appl. Microbiol. Biotechnol. 62:99-109(2003).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB
RC   10025;
RX   PubMed=12948626; DOI=10.1016/s0168-1656(03)00154-8;
RA   Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A.,
RA   Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A.,
RA   Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F.,
RA   Moeckel B., Pfefferle W., Puehler A., Rey D.A., Rueckert C., Rupp O.,
RA   Sahm H., Wendisch V.F., Wiegraebe I., Tauch A.;
RT   "The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its
RT   impact on the production of L-aspartate-derived amino acids and vitamins.";
RL   J. Biotechnol. 104:5-25(2003).
CC   -!- FUNCTION: Regulates arginine biosynthesis genes. {ECO:0000250}.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-arginine biosynthesis [regulation].
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ArgR family. {ECO:0000305}.
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DR   EMBL; AF049897; AAC24817.1; -; Genomic_DNA.
DR   EMBL; AF041436; AAD02198.1; -; Genomic_DNA.
DR   EMBL; BA000036; BAB98792.1; -; Genomic_DNA.
DR   EMBL; BX927152; CAF21410.1; -; Genomic_DNA.
DR   RefSeq; NP_600618.1; NC_003450.3.
DR   RefSeq; WP_003858683.1; NC_006958.1.
DR   AlphaFoldDB; O85175; -.
DR   SMR; O85175; -.
DR   STRING; 196627.cg1585; -.
DR   GeneID; 58310589; -.
DR   KEGG; cgb:cg1585; -.
DR   KEGG; cgl:Cgl1399; -.
DR   PATRIC; fig|196627.13.peg.1368; -.
DR   eggNOG; COG1438; Bacteria.
DR   HOGENOM; CLU_097103_1_1_11; -.
DR   OMA; IMGTICG; -.
DR   UniPathway; UPA00068; -.
DR   Proteomes; UP000000582; Chromosome.
DR   CollecTF; EXPREG_000006c0; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0032993; C:protein-DNA complex; IMP:CollecTF.
DR   GO; GO:0034618; F:arginine binding; IEA:InterPro.
DR   GO; GO:0001216; F:DNA-binding transcription activator activity; IMP:CollecTF.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IMP:CollecTF.
DR   GO; GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; EXP:CollecTF.
DR   GO; GO:0051259; P:protein complex oligomerization; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   HAMAP; MF_00173; Arg_repressor; 1.
DR   InterPro; IPR001669; Arg_repress.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR036251; Arg_repress_C_sf.
DR   InterPro; IPR020900; Arg_repress_DNA-bd.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR34471; PTHR34471; 1.
DR   Pfam; PF01316; Arg_repressor; 1.
DR   Pfam; PF02863; Arg_repressor_C; 1.
DR   PRINTS; PR01467; ARGREPRESSOR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF55252; SSF55252; 1.
DR   TIGRFAMs; TIGR01529; argR_whole; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..171
FT                   /note="Arginine repressor"
FT                   /id="PRO_0000205084"
FT   CONFLICT        138
FT                   /note="E -> Q (in Ref. 1; AAC24817)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   171 AA;  18468 MW;  9DA1206C75FE4CB1 CRC64;
     MSLGSTPSTP ENLNPVTRTA RQALILQILD KQKVTSQVQL SELLLDEGID ITQATLSRDL
     DELGARKVRP DGGRAYYAVG PVDSIAREDL RGPSEKLRRM LDELLVSTDH SGNIAMLRTP
     PGAAQYLASF IDRVGLKEVV GTIAGDDTVF VLARDPLTGK ELGELLSGRT T