ID   MDH1B_DANRE             Reviewed;         447 AA.
AC   Q08BZ4;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Putative malate dehydrogenase 1B;
DE            EC=1.1.1.-;
GN   Name=mdh1b; ORFNames=zgc:153922;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the LDH/MDH superfamily. MDH type 2 family.
CC       {ECO:0000305}.
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DR   EMBL; BC124491; AAI24492.1; -; mRNA.
DR   RefSeq; NP_001070229.1; NM_001076761.1.
DR   AlphaFoldDB; Q08BZ4; -.
DR   SMR; Q08BZ4; -.
DR   STRING; 7955.ENSDARP00000116491; -.
DR   PaxDb; Q08BZ4; -.
DR   GeneID; 767794; -.
DR   KEGG; dre:767794; -.
DR   CTD; 130752; -.
DR   ZFIN; ZDB-GENE-060929-384; mdh1b.
DR   eggNOG; KOG1496; Eukaryota.
DR   InParanoid; Q08BZ4; -.
DR   PRO; PR:Q08BZ4; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0030060; F:L-malate dehydrogenase activity; IBA:GO_Central.
DR   GO; GO:0006108; P:malate metabolic process; IBA:GO_Central.
DR   GO; GO:0006734; P:NADH metabolic process; IBA:GO_Central.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IBA:GO_Central.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IBA:GO_Central.
DR   Gene3D; 3.90.110.10; -; 1.
DR   InterPro; IPR022383; Lactate/malate_DH_C.
DR   InterPro; IPR015955; Lactate_DH/Glyco_Ohase_4_C.
DR   InterPro; IPR010945; Malate_DH_type2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR23382; PTHR23382; 2.
DR   Pfam; PF02866; Ldh_1_C; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   SUPFAM; SSF56327; SSF56327; 1.
PE   2: Evidence at transcript level;
KW   NAD; Oxidoreductase; Reference proteome; Tricarboxylic acid cycle.
FT   CHAIN           1..447
FT                   /note="Putative malate dehydrogenase 1B"
FT                   /id="PRO_0000331438"
SQ   SEQUENCE   447 AA;  50272 MW;  3107BC446C359A4F CRC64;
     MAKFVLAGKA DCPYYAKAEL LADVLQRNLP DFHIHKIPVP PDDWKEWLED TCASNGWKHS
     SSPLVWRELI DRGGKGMLLG GFSDFLEHAQ GYYGITSDMK SDLMLKIAEE NQATKELCME
     EEVHRLKSLR PLHIWISSAL NPVCYSLIPH LFTPGLFSGL PILSLHLMDT SGSEEMLQAL
     KMETVDLAIP RLHEPAGEYN DEQNDKDQVA EHFHRYGQLI ETNAQKDVRV LVAGDFFINM
     KCSLLIENAP SIDSRNFVAM TTQLEYEART QLAQKLSVKT SDITNVIVWG NISGSFHIDL
     QRAKVFRYDG AIRGPDGFSQ HVMEMIYDWK WLKTDFRSLL HKHRATISSK TNKATAISTT
     NAILAILKAW NNAESPEEVF SLGVLSTGQF GIPAGLVFSM PVSFTDGHWS VRSDVTVTDE
     LRVNLDACAD ELRMERDMAA KTLKNNA