MDJ1_SCHPO
ID MDJ1_SCHPO Reviewed; 528 AA.
AC P87239;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1997, sequence version 1.
DT 03-AUG-2022, entry version 136.
DE RecName: Full=DnaJ homolog 1, mitochondrial;
DE Flags: Precursor;
GN Name=mdj1; ORFNames=SPCC4G3.14;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329672; CAB09769.1; -; Genomic_DNA.
DR PIR; T41362; T41362.
DR RefSeq; NP_587824.1; NM_001022817.2.
DR AlphaFoldDB; P87239; -.
DR SMR; P87239; -.
DR BioGRID; 276064; 2.
DR STRING; 4896.SPCC4G3.14.1; -.
DR iPTMnet; P87239; -.
DR MaxQB; P87239; -.
DR PaxDb; P87239; -.
DR PRIDE; P87239; -.
DR EnsemblFungi; SPCC4G3.14.1; SPCC4G3.14.1:pep; SPCC4G3.14.
DR GeneID; 2539501; -.
DR KEGG; spo:SPCC4G3.14; -.
DR PomBase; SPCC4G3.14; mdj1.
DR VEuPathDB; FungiDB:SPCC4G3.14; -.
DR eggNOG; KOG0715; Eukaryota.
DR HOGENOM; CLU_017633_0_3_1; -.
DR InParanoid; P87239; -.
DR OMA; DLHCTVT; -.
DR PhylomeDB; P87239; -.
DR PRO; PR:P87239; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005743; C:mitochondrial inner membrane; ISO:PomBase.
DR GO; GO:0005739; C:mitochondrion; HDA:PomBase.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0030544; F:Hsp70 protein binding; ISM:PomBase.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0051082; F:unfolded protein binding; ISO:PomBase.
DR GO; GO:0051085; P:chaperone cofactor-dependent protein refolding; IBA:GO_Central.
DR GO; GO:0000002; P:mitochondrial genome maintenance; ISO:PomBase.
DR GO; GO:0042026; P:protein refolding; ISO:PomBase.
DR GO; GO:0009408; P:response to heat; IEA:InterPro.
DR CDD; cd06257; DnaJ; 1.
DR CDD; cd10719; DnaJ_zf; 1.
DR Gene3D; 1.10.287.110; -; 1.
DR HAMAP; MF_01152; DnaJ; 1.
DR InterPro; IPR012724; DnaJ.
DR InterPro; IPR002939; DnaJ_C.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR018253; DnaJ_domain_CS.
DR InterPro; IPR008971; HSP40/DnaJ_pept-bd.
DR InterPro; IPR001305; HSP_DnaJ_Cys-rich_dom.
DR InterPro; IPR036410; HSP_DnaJ_Cys-rich_dom_sf.
DR InterPro; IPR036869; J_dom_sf.
DR Pfam; PF00226; DnaJ; 1.
DR Pfam; PF01556; DnaJ_C; 1.
DR Pfam; PF00684; DnaJ_CXXCXGXG; 1.
DR PRINTS; PR00625; JDOMAIN.
DR SMART; SM00271; DnaJ; 1.
DR SUPFAM; SSF46565; SSF46565; 1.
DR SUPFAM; SSF49493; SSF49493; 2.
DR SUPFAM; SSF57938; SSF57938; 1.
DR PROSITE; PS00636; DNAJ_1; 1.
DR PROSITE; PS50076; DNAJ_2; 1.
DR PROSITE; PS51188; ZF_CR; 1.
PE 3: Inferred from homology;
KW Chaperone; Metal-binding; Mitochondrion; Reference proteome; Repeat;
KW Transit peptide; Zinc; Zinc-finger.
FT TRANSIT 1..66
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 67..528
FT /note="DnaJ homolog 1, mitochondrial"
FT /id="PRO_0000314109"
FT DOMAIN 86..150
FT /note="J"
FT REPEAT 240..247
FT /note="CXXCXGXG motif"
FT REPEAT 257..264
FT /note="CXXCXGXG motif"
FT REPEAT 280..287
FT /note="CXXCXGXG motif"
FT REPEAT 296..303
FT /note="CXXCXGXG motif"
FT ZN_FING 227..308
FT /note="CR-type"
FT REGION 455..528
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 455..498
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 509..528
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 528 AA; 57189 MW; DFD89C23CAD214CA CRC64;
MFSKYLQSRV CGLHSFTNSS AQQLFSKSIA HSSRRNFVIS SSCTKFRNVA IQRNAKREFS
RCAALKNFSY HARCFHATRA VWEMTDPYKT LGVSKSASAS EIKSAYYKLA KQYHPDANPD
KAAQDKFVEI KQAYEVLQDP KKKKAFDTYG AGAFKNGEFT GGDFEGFQNG FAGASSFSSG
FPGFNFEDLF GFSSRGPQAR RNTSFDVFVG EDIEASITID FMEAVRGAKK DLSYSVSSTC
SSCHGSGLQP GSHKSTCFAC KGTGQRLHFI PPSFHMQTTC DSCGGTGTTI PPNSACRSCM
GSGTVRERKT VSIDIPPGID DNTVLRVMGA GNDASTAKGG PNAKSRPGDL FATIHVRKHP
FFVREGTNVT YNAKIPMTTA ALGGTLRVPT LTGNVDLRVS PGTSTGDRIT MAGKGIRKVN
TSRYGNFYVN FEVTIPKILS PHERSLLEQL ADALNDSTAR RTQSSPSGTN SSTSTSSTSS
KHSTGISTEP TTGEENKQDG SVGGFFKRAF RRLHPDEDQN PKKDESSS
