MDM31_SCHPO
ID MDM31_SCHPO Reviewed; 601 AA.
AC Q10070;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 25-MAY-2022, entry version 113.
DE RecName: Full=Mitochondrial distribution and morphology protein 31;
DE Flags: Precursor;
GN Name=mdm31; ORFNames=SPAC3H1.04c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- FUNCTION: Involved in the organization of the mitochondrial membranes
CC and the global structure of the mitochondria. Also required for
CC mitochondrial distribution and mobility as well as for the maintenance
CC of mitochondrial DNA nucleoids structures (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000305};
CC Single-pass membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the MDM31/MDM32 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CU329670; CAA92257.1; -; Genomic_DNA.
DR PIR; T38736; T38736.
DR RefSeq; NP_593546.1; NM_001018979.2.
DR AlphaFoldDB; Q10070; -.
DR BioGRID; 279842; 32.
DR STRING; 4896.SPAC3H1.04c.1; -.
DR MaxQB; Q10070; -.
DR PaxDb; Q10070; -.
DR EnsemblFungi; SPAC3H1.04c.1; SPAC3H1.04c.1:pep; SPAC3H1.04c.
DR GeneID; 2543420; -.
DR KEGG; spo:SPAC3H1.04c; -.
DR PomBase; SPAC3H1.04c; mdm31.
DR VEuPathDB; FungiDB:SPAC3H1.04c; -.
DR eggNOG; ENOG502QQJG; Eukaryota.
DR HOGENOM; CLU_016236_2_1_1; -.
DR InParanoid; Q10070; -.
DR OMA; VFFCELP; -.
DR PhylomeDB; Q10070; -.
DR PRO; PR:Q10070; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005743; C:mitochondrial inner membrane; ISS:PomBase.
DR GO; GO:0005739; C:mitochondrion; IDA:PomBase.
DR GO; GO:0000001; P:mitochondrion inheritance; IEA:InterPro.
DR GO; GO:0007005; P:mitochondrion organization; IBA:GO_Central.
DR InterPro; IPR012571; Mdm31/Mdm32.
DR PANTHER; PTHR31068; PTHR31068; 1.
DR Pfam; PF08118; MDM31_MDM32; 2.
PE 3: Inferred from homology;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW Transit peptide; Transmembrane; Transmembrane helix.
FT TRANSIT 1..66
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 67..601
FT /note="Mitochondrial distribution and morphology protein
FT 31"
FT /id="PRO_0000116447"
FT TOPO_DOM 67..134
FT /note="Mitochondrial matrix"
FT /evidence="ECO:0000255"
FT TRANSMEM 135..155
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 156..601
FT /note="Mitochondrial intermembrane"
FT /evidence="ECO:0000255"
SQ SEQUENCE 601 AA; 69429 MW; 8E2857C8A35DB72E CRC64;
MLESRLAKNI ARIVQARKPY LISYHVRAST QNALLKQTVL QSSSFKSFPT LPRLAARNIS
NSGILSRTTP VIIKQISMVR SYSSGDVENP EILNKNESNQ SSGVKRAMPF RVLKKMKSFL
FKQNKPLTVD NVTAFFSWWL VSHIVWIVVG TTTFFSLLLY TLNTVSAQEL LGRWIGQLMT
KNTGFQFVFE SAIVPNWRKG LITFNKISVI RRPDTLNGIG AQNPNNKSDY EKEYMALRKR
YDSNEEPDTE ALSQGNYTQF ELSIDKADVS FSFARFLNGK GIVKELQLKG VRGVVDRRFI
EWDPSSDPRD YRRKHNWGDF EIEKFKLEDL RVTLLQPKGF RKFPVSVFFC ELPRLRKQWL
FYDLMNAKTL TGSFDNSMFT IHRLQLRPYS PYLKVGKQLD DMRHSRLRID NVAIDHLNRG
VSGAFGWIND GSVDFLVNIS FPSEPSENSF QKAWISLMDK LKKKEKDEDV YKDVHFDVNV
QLHNPKAVIP IFTNQVSYIN NALIRPIIAY INSTRTFIPI LCHVSKPLSD FDGSWTFYDS
GVLQEISAQV YESFARDVLN QEIRRKRIQK VGYWSLRRFL HLVLVSLQEL APTTSSISNF
E
