ID   MDM32_ASHGO             Reviewed;         577 AA.
AC   Q753C5;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Mitochondrial distribution and morphology protein 32;
DE   Flags: Precursor;
GN   Name=MDM32; OrderedLocusNames=AFR391W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Involved in the organization of the mitochondrial membranes
CC       and the global structure of the mitochondria. Also required for
CC       mitochondrial distribution and mobility as well as for the maintenance
CC       of mitochondrial DNA nucleoids structures (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MDM31/MDM32 family. {ECO:0000305}.
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DR   EMBL; AE016819; AAS53762.1; -; Genomic_DNA.
DR   RefSeq; NP_985938.1; NM_211293.1.
DR   AlphaFoldDB; Q753C5; -.
DR   STRING; 33169.AAS53762; -.
DR   EnsemblFungi; AAS53762; AAS53762; AGOS_AFR391W.
DR   GeneID; 4622210; -.
DR   KEGG; ago:AGOS_AFR391W; -.
DR   eggNOG; ENOG502QQU5; Eukaryota.
DR   HOGENOM; CLU_016236_3_0_1; -.
DR   InParanoid; Q753C5; -.
DR   OMA; FAKEMVG; -.
DR   Proteomes; UP000000591; Chromosome VI.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IBA:GO_Central.
DR   GO; GO:0006873; P:cellular ion homeostasis; IEA:EnsemblFungi.
DR   GO; GO:0000001; P:mitochondrion inheritance; IEA:EnsemblFungi.
DR   GO; GO:0007005; P:mitochondrion organization; IBA:GO_Central.
DR   InterPro; IPR012571; Mdm31/Mdm32.
DR   PANTHER; PTHR31068; PTHR31068; 1.
DR   Pfam; PF08118; MDM31_MDM32; 2.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transit peptide; Transmembrane; Transmembrane helix.
FT   TRANSIT         1..11
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           12..577
FT                   /note="Mitochondrial distribution and morphology protein
FT                   32"
FT                   /id="PRO_0000333677"
FT   TOPO_DOM        12..115
FT                   /note="Mitochondrial matrix"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        116..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        137..556
FT                   /note="Mitochondrial intermembrane"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        557..577
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   577 AA;  66127 MW;  844291F9A258DBEE CRC64;
     MLPVLRSGLR RAVWRCGHGL LQRRIAAGAG WYARACASDD AASRSPLKQE MLNSTEYLHV
     QNILLQKNQQ RMTKQKLLSE ATGFYDRFKI NTKWLLIRGN RPFSGEEIST LLSWLILSQV
     LWVILGTTTF VSLLLFLANT VLAKEMVGKF VGNSLNRYMD GVDVQFQDAM VPEWRKGQIS
     FQKVRLRTTP GAQDAGLLTF DLMFSKLSLT LSVRKWLQGR GLINDVYVSG MKGDVSVGAA
     ERKDAKLIDF FSNPNYELGE VEVCDSVIMC TDQEIGQKFR VSIYNMRMSQ LRFRWSLLDL
     FNADVVSGAL NHSLFSIHKR QHKLPLHEME KDMAPWKRIS RLRLNPISVK DLGLDKSNAF
     NWIEGGSVEM IADLMLPNIY PESAAAEDEN KYVVMDLRIT FKDLIASMNT VPPALSNGRE
     LISFDELKPI IMFVNNRRGL FSSLRNLDNN KLWRPTVTIE RQQSYPDTTV IPMRTFQWPE
     GEGSVQLNQE IIKYHENPSD NSNEIILRCR IAKHMNELQN TFLFKETDVY DKMALELYTD
     LMKMIEETEY KKKNDWVKLL GTTFASQLLI FGLGAMV