ID   MDM32_VANPO             Reviewed;         676 AA.
AC   A7THL9;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Mitochondrial distribution and morphology protein 32;
DE   Flags: Precursor;
GN   Name=MDM32; ORFNames=Kpol_543p14;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: Involved in the organization of the mitochondrial membranes
CC       and the global structure of the mitochondria. Also required for
CC       mitochondrial distribution and mobility as well as for the maintenance
CC       of mitochondrial DNA nucleoids structures (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MDM31/MDM32 family. {ECO:0000305}.
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DR   EMBL; DS480392; EDO18185.1; -; Genomic_DNA.
DR   RefSeq; XP_001646043.1; XM_001645993.1.
DR   AlphaFoldDB; A7THL9; -.
DR   STRING; 436907.A7THL9; -.
DR   EnsemblFungi; EDO18185; EDO18185; Kpol_543p14.
DR   GeneID; 5546459; -.
DR   KEGG; vpo:Kpol_543p14; -.
DR   eggNOG; ENOG502QQU5; Eukaryota.
DR   HOGENOM; CLU_016236_3_0_1; -.
DR   InParanoid; A7THL9; -.
DR   OMA; FAKEMVG; -.
DR   OrthoDB; 843310at2759; -.
DR   PhylomeDB; A7THL9; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000001; P:mitochondrion inheritance; IEA:InterPro.
DR   InterPro; IPR012571; Mdm31/Mdm32.
DR   PANTHER; PTHR31068; PTHR31068; 1.
DR   Pfam; PF08118; MDM31_MDM32; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transit peptide; Transmembrane; Transmembrane helix.
FT   TRANSIT         1..17
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..676
FT                   /note="Mitochondrial distribution and morphology protein
FT                   32"
FT                   /id="PRO_0000333680"
FT   TOPO_DOM        18..183
FT                   /note="Mitochondrial matrix"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        184..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        205..655
FT                   /note="Mitochondrial intermembrane"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        656..676
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   676 AA;  77502 MW;  D0A41A8C36BB5A83 CRC64;
     MAGLLPRAYG GVLRRSYIYL GSQCSNSVSR LTVGSTFRLV RMKSWGTSKF HTNGSPVLNE
     IKKISKSNGI TIINPLVNKV TTNNVSTSSN GKAAVAAATA ATAVSLGSTG QDDALSRNTD
     FLHIQNILLQ KNQDRMNKQK LLSEATNFYE RFKINTKWLL IRGNRPFSAD EIGTLFSWII
     LSQILWIILG TTTFVSILLI IFNTVFAKEM VGNVVGKLLN IFLDGIDVKF QDALVPEWRK
     GCIRFNNVQL RTHPLQASEP ENINDYNELV NNMIEFDLKL HQIELSLSLK KWLLGNGLIQ
     DLTIMGMRGN ITVTPVSLEN KIDDNQRVNL IDWFSNPYYH LGNVKVTDSS IILHDNQLSK
     DFKVSIYNLD MPQLRFQWII NDFLSSNVVD GSINHSLFNI HKRQHKLAYI KDLENDLSDW
     KRITRIRLDS IDVKKLGLNN SNAFNWMDDG QLDIIADVML PNEQENEPDF DFTRNKKEHM
     SKSNNKYVVL DLKFRFKDLK AIFPDRAPRL SNGEEILSLD ELKQIILFIN RKYDLYHSYA
     NSSYKNTLWD APNIAINKAK SFPVTTVFQS KKDFSNEDSD EEDRKLKKQI IRFHDDISTP
     NNELVLSCKV VKNINELKNM VLFWETGIYD SLSMELYIDL MKMVEEWEYK KKTNWMTDWG
     SSVASQLIIV GFGAMV