ID   MDTI_PHOLL              Reviewed;         109 AA.
AC   Q7N536;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Spermidine export protein MdtI {ECO:0000255|HAMAP-Rule:MF_01597};
GN   Name=mdtI {ECO:0000255|HAMAP-Rule:MF_01597}; OrderedLocusNames=plu2124;
OS   Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 /
OS   TT01).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Photorhabdus.
OX   NCBI_TaxID=243265;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15139 / CIP 105565 / TT01;
RX   PubMed=14528314; DOI=10.1038/nbt886;
RA   Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A.,
RA   Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F.,
RA   Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C.,
RA   Lanois A., Powell K., Siguier P., Vincent R., Wingate V., Zouine M.,
RA   Glaser P., Boemare N., Danchin A., Kunst F.;
RT   "The genome sequence of the entomopathogenic bacterium Photorhabdus
RT   luminescens.";
RL   Nat. Biotechnol. 21:1307-1313(2003).
CC   -!- FUNCTION: Catalyzes the excretion of spermidine. {ECO:0000255|HAMAP-
CC       Rule:MF_01597}.
CC   -!- SUBUNIT: Forms a complex with MdtJ. {ECO:0000255|HAMAP-Rule:MF_01597}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01597}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01597}.
CC   -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC       superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01597}.
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DR   EMBL; BX571866; CAE14417.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q7N536; -.
DR   SMR; Q7N536; -.
DR   STRING; 243265.plu2124; -.
DR   EnsemblBacteria; CAE14417; CAE14417; plu2124.
DR   KEGG; plu:plu2124; -.
DR   eggNOG; COG2076; Bacteria.
DR   HOGENOM; CLU_133067_0_4_6; -.
DR   OMA; VAAGWIM; -.
DR   Proteomes; UP000002514; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR   GO; GO:0015606; F:spermidine transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR   HAMAP; MF_01597; MdtI; 1.
DR   InterPro; IPR000390; Small_drug/metabolite_transptr.
DR   InterPro; IPR045324; Small_multidrug_res.
DR   InterPro; IPR023737; Spermidine_export_MdtI.
DR   PANTHER; PTHR30561; PTHR30561; 1.
DR   PANTHER; PTHR30561:SF6; PTHR30561:SF6; 1.
DR   Pfam; PF00893; Multi_Drug_Res; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..109
FT                   /note="Spermidine export protein MdtI"
FT                   /id="PRO_0000331143"
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01597"
FT   TRANSMEM        36..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01597"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01597"
FT   TRANSMEM        88..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01597"
SQ   SEQUENCE   109 AA;  11999 MW;  70163F4366AAF917 CRC64;
     MQQFEWWHAA FLFLAVVLDI LANILLKLSN GFRRPWMGIL SLIAVLGAFS ALAQAVKGIE
     LSIAYALWGA FGIIATVAAG WIMFNQRLNY KGWGGIALLL LGMVMIKMA