ID   MDTJ_CROS8              Reviewed;         119 AA.
AC   A7MEJ4;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Spermidine export protein MdtJ;
GN   Name=mdtJ; OrderedLocusNames=ESA_01729;
OS   Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Cronobacter.
OX   NCBI_TaxID=290339;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-894;
RX   PubMed=20221447; DOI=10.1371/journal.pone.0009556;
RA   Kucerova E., Clifton S.W., Xia X.Q., Long F., Porwollik S., Fulton L.,
RA   Fronick C., Minx P., Kyung K., Warren W., Fulton R., Feng D., Wollam A.,
RA   Shah N., Bhonagiri V., Nash W.E., Hallsworth-Pepin K., Wilson R.K.,
RA   McClelland M., Forsythe S.J.;
RT   "Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic
RT   hybridization analysis with other Cronobacter species.";
RL   PLoS ONE 5:E9556-E9556(2010).
CC   -!- FUNCTION: Catalyzes the excretion of spermidine. {ECO:0000250}.
CC   -!- SUBUNIT: Forms a complex with MdtI. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC       superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01598}.
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DR   EMBL; CP000783; ABU76983.1; -; Genomic_DNA.
DR   RefSeq; WP_007868015.1; NC_009778.1.
DR   AlphaFoldDB; A7MEJ4; -.
DR   SMR; A7MEJ4; -.
DR   EnsemblBacteria; ABU76983; ABU76983; ESA_01729.
DR   GeneID; 56730551; -.
DR   KEGG; esa:ESA_01729; -.
DR   HOGENOM; CLU_133067_0_0_6; -.
DR   OMA; MRSWIYL; -.
DR   OrthoDB; 1921902at2; -.
DR   Proteomes; UP000000260; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR   GO; GO:0015606; F:spermidine transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR   InterPro; IPR000390; Small_drug/metabolite_transptr.
DR   InterPro; IPR045324; Small_multidrug_res.
DR   InterPro; IPR023740; Spermidine_export_MdtJ.
DR   PANTHER; PTHR30561; PTHR30561; 1.
DR   PANTHER; PTHR30561:SF2; PTHR30561:SF2; 1.
DR   Pfam; PF00893; Multi_Drug_Res; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..119
FT                   /note="Spermidine export protein MdtJ"
FT                   /id="PRO_0000331164"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        31..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   119 AA;  12753 MW;  E2F00BBEEE3344B9 CRC64;
     MIYWILLALA IVSEITGTLA LKWASVGGGH AGFILMLVMI SLSYILLSFS VKRIALGVAY
     ALWEGVGIVL ITLFSVLLFN ETLTVQKALG LLVLIAGILL IKTGTRTVSR KAEVRHVAG