ID   MDTJ_PHOLL              Reviewed;         138 AA.
AC   Q7N537;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=Spermidine export protein MdtJ {ECO:0000255|HAMAP-Rule:MF_01598};
GN   Name=mdtJ {ECO:0000255|HAMAP-Rule:MF_01598}; OrderedLocusNames=plu2123;
OS   Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 /
OS   TT01).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Photorhabdus.
OX   NCBI_TaxID=243265;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15139 / CIP 105565 / TT01;
RX   PubMed=14528314; DOI=10.1038/nbt886;
RA   Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A.,
RA   Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F.,
RA   Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C.,
RA   Lanois A., Powell K., Siguier P., Vincent R., Wingate V., Zouine M.,
RA   Glaser P., Boemare N., Danchin A., Kunst F.;
RT   "The genome sequence of the entomopathogenic bacterium Photorhabdus
RT   luminescens.";
RL   Nat. Biotechnol. 21:1307-1313(2003).
CC   -!- FUNCTION: Catalyzes the excretion of spermidine. {ECO:0000255|HAMAP-
CC       Rule:MF_01598}.
CC   -!- SUBUNIT: Forms a complex with MdtI. {ECO:0000255|HAMAP-Rule:MF_01598}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01598}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01598}.
CC   -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC       superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01598}.
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DR   EMBL; BX571866; CAE14416.1; -; Genomic_DNA.
DR   RefSeq; WP_011146377.1; NC_005126.1.
DR   AlphaFoldDB; Q7N537; -.
DR   SMR; Q7N537; -.
DR   STRING; 243265.plu2123; -.
DR   PRIDE; Q7N537; -.
DR   EnsemblBacteria; CAE14416; CAE14416; plu2123.
DR   GeneID; 24166515; -.
DR   KEGG; plu:plu2123; -.
DR   eggNOG; COG2076; Bacteria.
DR   HOGENOM; CLU_133067_0_0_6; -.
DR   OMA; MRSWIYL; -.
DR   OrthoDB; 1921902at2; -.
DR   BioCyc; PLUM243265:PLU_RS10605-MON; -.
DR   Proteomes; UP000002514; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR   GO; GO:0015606; F:spermidine transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR   HAMAP; MF_01598; MdtJ; 1.
DR   InterPro; IPR000390; Small_drug/metabolite_transptr.
DR   InterPro; IPR045324; Small_multidrug_res.
DR   InterPro; IPR023740; Spermidine_export_MdtJ.
DR   PANTHER; PTHR30561; PTHR30561; 1.
DR   PANTHER; PTHR30561:SF2; PTHR30561:SF2; 1.
DR   Pfam; PF00893; Multi_Drug_Res; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..138
FT                   /note="Spermidine export protein MdtJ"
FT                   /id="PRO_0000331172"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01598"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01598"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01598"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01598"
SQ   SEQUENCE   138 AA;  14725 MW;  8AC4C9A5133E8C98 CRC64;
     MIYWLFLAMA IITEVIGTLS MKHASVSGGV VGMAVMYIMI ATSYILLAMA VKKVALGVAY
     ALWEGVGILF ITVFSVMWFD ESLSLMKVGG LALLITGIML IKSGTRKAAV KKSAEVVKQM
     ANKAVSVATT KSSKIKEA