ID   MDTJ_SALHS              Reviewed;         120 AA.
AC   B4THR3;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Spermidine export protein MdtJ {ECO:0000255|HAMAP-Rule:MF_01598};
GN   Name=mdtJ {ECO:0000255|HAMAP-Rule:MF_01598}; OrderedLocusNames=SeHA_C1651;
OS   Salmonella heidelberg (strain SL476).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=454169;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SL476;
RX   PubMed=21602358; DOI=10.1128/jb.00297-11;
RA   Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G.,
RA   Leclerc J.E., Ravel J., Cebula T.A.;
RT   "Comparative genomics of 28 Salmonella enterica isolates: evidence for
RT   CRISPR-mediated adaptive sublineage evolution.";
RL   J. Bacteriol. 193:3556-3568(2011).
CC   -!- FUNCTION: Catalyzes the excretion of spermidine. {ECO:0000255|HAMAP-
CC       Rule:MF_01598}.
CC   -!- SUBUNIT: Forms a complex with MdtI. {ECO:0000255|HAMAP-Rule:MF_01598}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01598}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01598}.
CC   -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC       superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01598}.
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DR   EMBL; CP001120; ACF68578.1; -; Genomic_DNA.
DR   RefSeq; WP_000500278.1; NC_011083.1.
DR   AlphaFoldDB; B4THR3; -.
DR   SMR; B4THR3; -.
DR   KEGG; seh:SeHA_C1651; -.
DR   HOGENOM; CLU_133067_0_0_6; -.
DR   OMA; MRSWIYL; -.
DR   Proteomes; UP000001866; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR   GO; GO:0015606; F:spermidine transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR   HAMAP; MF_01598; MdtJ; 1.
DR   InterPro; IPR000390; Small_drug/metabolite_transptr.
DR   InterPro; IPR045324; Small_multidrug_res.
DR   InterPro; IPR023740; Spermidine_export_MdtJ.
DR   PANTHER; PTHR30561; PTHR30561; 1.
DR   PANTHER; PTHR30561:SF2; PTHR30561:SF2; 1.
DR   Pfam; PF00893; Multi_Drug_Res; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..120
FT                   /note="Spermidine export protein MdtJ"
FT                   /id="PRO_1000197338"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01598"
FT   TRANSMEM        31..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01598"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01598"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01598"
SQ   SEQUENCE   120 AA;  12915 MW;  FE22DD49654532BC CRC64;
     MFYWILLALA IATEITGTLS MKWASVGNGN AGFILMLVMI TLSYIFLSFA VKKIALGVAY
     ALWEGIGILF ITIFSVLLFD EALSTMKIAG LLTLVAGIVL IKSGTRKPGK PVKEATRATI