ID   MDTJ_YERP3              Reviewed;         147 AA.
AC   A7FIB5;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Spermidine export protein MdtJ {ECO:0000255|HAMAP-Rule:MF_01598};
GN   Name=mdtJ {ECO:0000255|HAMAP-Rule:MF_01598};
GN   OrderedLocusNames=YpsIP31758_2020;
OS   Yersinia pseudotuberculosis serotype O:1b (strain IP 31758).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=349747;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IP 31758;
RX   PubMed=17784789; DOI=10.1371/journal.pgen.0030142;
RA   Eppinger M., Rosovitz M.J., Fricke W.F., Rasko D.A., Kokorina G.,
RA   Fayolle C., Lindler L.E., Carniel E., Ravel J.;
RT   "The complete genome sequence of Yersinia pseudotuberculosis IP31758, the
RT   causative agent of Far East scarlet-like fever.";
RL   PLoS Genet. 3:1508-1523(2007).
CC   -!- FUNCTION: Catalyzes the excretion of spermidine. {ECO:0000255|HAMAP-
CC       Rule:MF_01598}.
CC   -!- SUBUNIT: Forms a complex with MdtI. {ECO:0000255|HAMAP-Rule:MF_01598}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01598}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01598}.
CC   -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC       superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01598}.
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DR   EMBL; CP000720; ABS47628.1; -; Genomic_DNA.
DR   RefSeq; WP_012105125.1; NC_009708.1.
DR   AlphaFoldDB; A7FIB5; -.
DR   SMR; A7FIB5; -.
DR   EnsemblBacteria; ABS47628; ABS47628; YpsIP31758_2020.
DR   KEGG; ypi:YpsIP31758_2020; -.
DR   HOGENOM; CLU_133067_0_0_6; -.
DR   OMA; MRSWIYL; -.
DR   Proteomes; UP000002412; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR   GO; GO:0015606; F:spermidine transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR   HAMAP; MF_01598; MdtJ; 1.
DR   InterPro; IPR000390; Small_drug/metabolite_transptr.
DR   InterPro; IPR045324; Small_multidrug_res.
DR   InterPro; IPR023740; Spermidine_export_MdtJ.
DR   PANTHER; PTHR30561; PTHR30561; 1.
DR   PANTHER; PTHR30561:SF2; PTHR30561:SF2; 1.
DR   Pfam; PF00893; Multi_Drug_Res; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..147
FT                   /note="Spermidine export protein MdtJ"
FT                   /id="PRO_0000331191"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01598"
FT   TRANSMEM        31..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01598"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01598"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01598"
FT   REGION          105..147
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   147 AA;  15833 MW;  3A9FCFAA4F95D24C CRC64;
     MIYWIFLGLA IIAEIIGTLS MKYASVSGEM TGHIVMYFMI TGSYVMLSLA VKKVALGVAY
     ALWEGIGILI ITIFSVMWFG ETLSPLKIAG LVTLIGGILL VKSGTRKPKQ PNRHRGNRPP
     SVQGLKTQTT GHHKGVAVES GEHHAAA