ID   MDV1_SCLS1              Reviewed;         667 AA.
AC   A7ETB3;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Mitochondrial division protein 1;
GN   Name=mdv1; ORFNames=SS1G_08568;
OS   Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold)
OS   (Whetzelinia sclerotiorum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Sclerotiniaceae; Sclerotinia.
OX   NCBI_TaxID=665079;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 18683 / 1980 / Ss-1;
RX   PubMed=21876677; DOI=10.1371/journal.pgen.1002230;
RA   Amselem J., Cuomo C.A., van Kan J.A.L., Viaud M., Benito E.P., Couloux A.,
RA   Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., Fournier E.,
RA   Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., Pradier J.-M.,
RA   Quevillon E., Sharon A., Simon A., ten Have A., Tudzynski B., Tudzynski P.,
RA   Wincker P., Andrew M., Anthouard V., Beever R.E., Beffa R., Benoit I.,
RA   Bouzid O., Brault B., Chen Z., Choquer M., Collemare J., Cotton P.,
RA   Danchin E.G., Da Silva C., Gautier A., Giraud C., Giraud T., Gonzalez C.,
RA   Grossetete S., Gueldener U., Henrissat B., Howlett B.J., Kodira C.,
RA   Kretschmer M., Lappartient A., Leroch M., Levis C., Mauceli E.,
RA   Neuveglise C., Oeser B., Pearson M., Poulain J., Poussereau N.,
RA   Quesneville H., Rascle C., Schumacher J., Segurens B., Sexton A., Silva E.,
RA   Sirven C., Soanes D.M., Talbot N.J., Templeton M., Yandava C., Yarden O.,
RA   Zeng Q., Rollins J.A., Lebrun M.-H., Dickman M.;
RT   "Genomic analysis of the necrotrophic fungal pathogens Sclerotinia
RT   sclerotiorum and Botrytis cinerea.";
RL   PLoS Genet. 7:E1002230-E1002230(2011).
CC   -!- FUNCTION: Involved in mitochondrial fission. Acts as an adapter protein
CC       required to form mitochondrial fission complexes. Formation of these
CC       complexes is required to promote constriction and fission of the
CC       mitochondrial compartment at a late step in mitochondrial division (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Cytoplasmic side
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat MDV1/CAF4 family. {ECO:0000305}.
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DR   EMBL; CH476631; EDN92705.1; -; Genomic_DNA.
DR   RefSeq; XP_001590828.1; XM_001590778.1.
DR   AlphaFoldDB; A7ETB3; -.
DR   SMR; A7ETB3; -.
DR   STRING; 665079.A7ETB3; -.
DR   PRIDE; A7ETB3; -.
DR   EnsemblFungi; EDN92705; EDN92705; SS1G_08568.
DR   GeneID; 5486691; -.
DR   KEGG; ssl:SS1G_08568; -.
DR   eggNOG; KOG4155; Eukaryota.
DR   HOGENOM; CLU_012350_1_1_1; -.
DR   InParanoid; A7ETB3; -.
DR   OMA; IVGVWTC; -.
DR   Proteomes; UP000001312; Unassembled WGS sequence.
DR   GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0000266; P:mitochondrial fission; IBA:GO_Central.
DR   GO; GO:0016559; P:peroxisome fission; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 4.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 3.
DR   PROSITE; PS50082; WD_REPEATS_2; 5.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Membrane; Mitochondrion; Mitochondrion outer membrane;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..667
FT                   /note="Mitochondrial division protein 1"
FT                   /id="PRO_0000330111"
FT   REPEAT          319..360
FT                   /note="WD 1"
FT   REPEAT          361..398
FT                   /note="WD 2"
FT   REPEAT          442..481
FT                   /note="WD 3"
FT   REPEAT          501..546
FT                   /note="WD 4"
FT   REPEAT          549..586
FT                   /note="WD 5"
FT   REPEAT          588..625
FT                   /note="WD 6"
FT   REPEAT          628..666
FT                   /note="WD 7"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          131..167
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          276..295
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          166..253
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   667 AA;  73915 MW;  63DF04354481DA4B CRC64;
     MAGSSSRNAS SFGAEEDEDG ALISTRGLEA FGRKVTTTAG HLIGPIDPTS STHYQNAMSD
     LHKQLRRPNL QRSVFSFAKT TPTDLVRSKL STSEIQYRAL TFLPDELLRN IPENENSYSL
     FQGFQASLPE AGEEKGKKHR RRISRGRKLI DNASEGGSEG DGPPSVAKLK KEKEALNHRL
     EMMGIRKNMA SSEIHGIDNK IANLNSMRRI VLDRLAGLEQ EESMLEHENV ENRLEEAQEQ
     IEDAEALGKS IVGAEEGDDV ENSGMESSFM SESIYEKLPS SASTSSSKGS RRHKTIRRKS
     MPILHEHFEP GSSIREIQAH DDMVTALDFD VPFGTMVSSA LDDTVRVWDM NAGRCMGLLE
     GHTASVRTLQ VEDNIVATGS MDATIRLWDL SKARYDPQDK IKEEQEEGEE DQLAFGEALE
     REQQTHIPQG TMQDCPLFTL EAHVDEVTAL HFRGDTLISG SADKTLRQWD LEKGRCVQTL
     DVMWAAAQAS ATMGSTEGTW RQTGRLPDAT ADFVGAVQVF DAALACGTAD GMVRLWDLRS
     GQVHRSLVGH TGPVTCLQFD DVHLVTGSLD RSIRIWDLRT GAIYDAYAYD APITSMMFDT
     RRIVAAAGED MVKVYDKTDG RHWDCGIGAQ REASEEMVER NIIEKCRVKD GYMVEGRRSG
     MVGIWSC