ID   MDV1_USTMA              Reviewed;         814 AA.
AC   Q4P8R5; A0A0D1C3W8;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Mitochondrial division protein 1;
GN   Name=MDV1; ORFNames=UMAG_03498;
OS   Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=237631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=521 / FGSC 9021;
RX   PubMed=17080091; DOI=10.1038/nature05248;
RA   Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA   Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA   Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA   Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA   Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA   Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA   Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA   Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA   Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA   Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA   Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA   Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA   Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA   Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA   Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA   Birren B.W.;
RT   "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT   maydis.";
RL   Nature 444:97-101(2006).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=521 / FGSC 9021;
RA   Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G., Kahmann R.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in mitochondrial fission. Acts as an adapter protein
CC       required to form mitochondrial fission complexes. Formation of these
CC       complexes is required to promote constriction and fission of the
CC       mitochondrial compartment at a late step in mitochondrial division (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Cytoplasmic side
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat MDV1/CAF4 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CM003148; KIS68407.1; -; Genomic_DNA.
DR   RefSeq; XP_011389947.1; XM_011391645.1.
DR   AlphaFoldDB; Q4P8R5; -.
DR   SMR; Q4P8R5; -.
DR   STRING; 5270.UM03498P0; -.
DR   EnsemblFungi; KIS68407; KIS68407; UMAG_03498.
DR   GeneID; 23563934; -.
DR   KEGG; uma:UMAG_03498; -.
DR   VEuPathDB; FungiDB:UMAG_03498; -.
DR   eggNOG; KOG4155; Eukaryota.
DR   HOGENOM; CLU_012350_0_0_1; -.
DR   InParanoid; Q4P8R5; -.
DR   OMA; GVRMWDM; -.
DR   OrthoDB; 927943at2759; -.
DR   Proteomes; UP000000561; Chromosome 9.
DR   GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0017053; C:transcription repressor complex; IBA:GO_Central.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 3.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 5.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 4.
DR   PROSITE; PS50082; WD_REPEATS_2; 6.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Membrane; Mitochondrion; Mitochondrion outer membrane;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..814
FT                   /note="Mitochondrial division protein 1"
FT                   /id="PRO_0000330112"
FT   REPEAT          411..450
FT                   /note="WD 1"
FT   REPEAT          453..490
FT                   /note="WD 2"
FT   REPEAT          554..591
FT                   /note="WD 3"
FT   REPEAT          659..702
FT                   /note="WD 4"
FT   REPEAT          705..742
FT                   /note="WD 5"
FT   REPEAT          744..781
FT                   /note="WD 6"
FT   REPEAT          785..814
FT                   /note="WD 7"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          365..394
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          499..542
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          608..631
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          270..303
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   814 AA;  87992 MW;  7E46B34E52BCE6EA CRC64;
     MSYSPLLGAD RRAGEPSSGL ASSTSIRDTL SGALNSTKAY LQPFTPASPY LGSNGVNGHN
     EPSRLLSDVA PQLMTTRMMA AVTNSNTALG LTPDGQRRAR LLLTPGFSIT SPARSLVRIG
     GSLIQSGIGR GPMNGITSNE LFVLEESDRI LATAARDLDL EANADAQLGA RSAIEASKSK
     AAEPSVSLLR GFQATIPSST EGRQRRRRVR ALASGFEDGP EGPTKLGLKA MGDKARGLMV
     EGVDAEPVSA FQAREQRHAR RNQASRILSR AKEGSRSSAI QLEELERQLR EIEREQGDVG
     VRRSLIDSEM AAVDDKIKVL ENIKAGLHKK LLGLREEELE LNDEHEGVGE LLAVQKHLRA
     MPGGPAAAAN AAASGGATTS QGSSRRRKGP LFMPSEHDEL PSGVAFMTLA DHSAPITSLD
     FTEPYGTLVS ASLDETVRVW DLASGEEVGR LRGHVGTVKC LQVEDEVCIT GGSDHSIRIW
     DLTKVENFEA RLTMTASGEL RARRRSPDLN RSPPPVADES MDSIKIRDGD TTAGDGDEEE
     VRDEFDPCVK RLEGHSKSVT SLYFDDNCLV TGASDKTLRQ WDLNTGQCVL TMDILWAISN
     PTSSQAISQS EFGFPESPSR KASSSSILGA TRPDLSSRDS FSVLNNLSGA FSYPTPPYAD
     GSWEMYQDFV GGVQFWGYAL ASGSGDGGVR MWDMRTGQAH RTLLGHTAPV TCLQFDEHHI
     ISGSLDKSIR IWDLRMGSIS DTVRYEHPVT ALQFDSRKIL AATGENGVKL FNRTTLQHGS
     LTLNGHTSPV ERLRYMDRYA VSGGKDCVVK IWAL