MDXF_BACSU
ID MDXF_BACSU Reviewed; 435 AA.
AC O06990; Q795G9;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1997, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Maltodextrin transport system permease protein MdxF;
GN Name=mdxF; Synonyms=yvdH; OrderedLocusNames=BSU34600;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Denizot F.;
RL Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP FUNCTION, AND NOMENCLATURE.
RC STRAIN=168;
RX PubMed=16707683; DOI=10.1128/jb.00213-06;
RA Schoenert S., Seitz S., Krafft H., Feuerbaum E.-A., Andernach I., Witz G.,
RA Dahl M.K.;
RT "Maltose and maltodextrin utilization by Bacillus subtilis.";
RL J. Bacteriol. 188:3911-3922(2006).
CC -!- FUNCTION: Part of the ABC transporter complex involved in maltodextrin
CC import. Probably responsible for the translocation of the substrate
CC across the membrane (Probable). {ECO:0000305|PubMed:16707683}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (MsmX),
CC two transmembrane proteins (MdxF and MdxG) and a solute-binding protein
CC (MdxE). {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. MalFG subfamily. {ECO:0000305}.
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DR EMBL; Z94043; CAB08037.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB15465.1; -; Genomic_DNA.
DR PIR; H70033; H70033.
DR RefSeq; NP_391340.1; NC_000964.3.
DR RefSeq; WP_003243114.1; NZ_JNCM01000033.1.
DR AlphaFoldDB; O06990; -.
DR SMR; O06990; -.
DR STRING; 224308.BSU34600; -.
DR TCDB; 3.A.1.1.26; the atp-binding cassette (abc) superfamily.
DR PaxDb; O06990; -.
DR PRIDE; O06990; -.
DR EnsemblBacteria; CAB15465; CAB15465; BSU_34600.
DR GeneID; 937063; -.
DR KEGG; bsu:BSU34600; -.
DR PATRIC; fig|224308.179.peg.3747; -.
DR eggNOG; COG1175; Bacteria.
DR InParanoid; O06990; -.
DR OMA; WYAYAMI; -.
DR PhylomeDB; O06990; -.
DR BioCyc; BSUB:BSU34600-MON; -.
DR SABIO-RK; O06990; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:1990060; C:maltose transport complex; IBA:GO_Central.
DR GO; GO:0015423; F:ABC-type maltose transporter activity; IBA:GO_Central.
DR GO; GO:0042956; P:maltodextrin transmembrane transport; IBA:GO_Central.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR030156; MalF-like.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR PANTHER; PTHR47314:SF1; PTHR47314:SF1; 2.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; SSF161098; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Polysaccharide transport; Reference proteome;
KW Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..435
FT /note="Maltodextrin transport system permease protein MdxF"
FT /id="PRO_0000361678"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 73..93
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 136..156
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 234..254
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 293..313
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 337..357
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 403..423
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 195..422
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 435 AA; 48529 MW; 31E86E8B0E7797DC CRC64;
MNKHHTLTKQ KRKAGLLSII PGLGQIANQQ LSKGLLFLAI TGLFAFELCV FGIQALTGLM
TLGSVPGEDH SLFMLIEGTL QLIVTMIFLM FYIFNIHDSR KTAAMKAAGL EVNTTAKDMI
CHAGDKGFPY LFTLPAYIMM VFVIIFPVLV TLFVALTNYD FYHIPPNRLI DWVGFKNFLN
IFFLGSYRET FVNVLGWTVI WTICATTLQI ILGIVTALFV NQDFIKGKRI FRMIFLFPWA
VPAFITIMSF SNMFNDSIGA VNAQVIPLFN HLPFVELPAI AWKTDPFWTK TALIMIQTWL
GFPYIYVMVT GVLQAIPGEL YEAAKIDGAT FIQRFRHITF PMILFATAPV MITQYTFNFN
NFSIIYLFNE GGPGSAGAGA GSTDILISWI YKLTTGTSPQ YSVAAAVTLL ISFIVIGISL
IAFKKSNAFG NEEVM
