MEA1_PIG
ID MEA1_PIG Reviewed; 174 AA.
AC Q95313; A5GFR0;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 16-JUN-2009, sequence version 2.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=Male-enhanced antigen 1;
DE Short=MEA-1;
GN Name=MEA1; Synonyms=MEA;
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Porcine genome sequencing project;
RL Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-113.
RC TISSUE=Small intestine;
RX PubMed=8672129; DOI=10.1007/s003359900153;
RA Winteroe A.K., Fredholm M., Davies W.;
RT "Evaluation and characterization of a porcine small intestine cDNA library:
RT analysis of 839 clones.";
RL Mamm. Genome 7:509-517(1996).
CC -!- FUNCTION: May play an important role in spermatogenesis and/or testis
CC development.
CC -!- CAUTION: It is uncertain whether Met-1 or Met-11 is the initiator.
CC {ECO:0000305}.
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DR EMBL; CR956379; CAN13172.1; -; Genomic_DNA.
DR EMBL; Z81165; CAB03550.1; -; mRNA.
DR RefSeq; NP_001103899.1; NM_001110429.1.
DR RefSeq; XP_005666041.1; XM_005665984.2.
DR RefSeq; XP_005666042.1; XM_005665985.2.
DR RefSeq; XP_013833375.1; XM_013977921.1.
DR RefSeq; XP_013833376.1; XM_013977922.1.
DR RefSeq; XP_013833377.1; XM_013977923.1.
DR AlphaFoldDB; Q95313; -.
DR STRING; 9823.ENSSSCP00000001794; -.
DR PaxDb; Q95313; -.
DR PeptideAtlas; Q95313; -.
DR Ensembl; ENSSSCT00000073227; ENSSSCP00000060822; ENSSSCG00000001655.
DR Ensembl; ENSSSCT00005060640; ENSSSCP00005037452; ENSSSCG00005037935.
DR Ensembl; ENSSSCT00005060687; ENSSSCP00005037483; ENSSSCG00005037935.
DR Ensembl; ENSSSCT00015034524; ENSSSCP00015013664; ENSSSCG00015025979.
DR Ensembl; ENSSSCT00025057337; ENSSSCP00025024246; ENSSSCG00025042272.
DR Ensembl; ENSSSCT00030084952; ENSSSCP00030039128; ENSSSCG00030060727.
DR Ensembl; ENSSSCT00035052486; ENSSSCP00035021107; ENSSSCG00035039487.
DR Ensembl; ENSSSCT00035052489; ENSSSCP00035021110; ENSSSCG00035039487.
DR Ensembl; ENSSSCT00040070483; ENSSSCP00040030020; ENSSSCG00040051755.
DR Ensembl; ENSSSCT00040070530; ENSSSCP00040030040; ENSSSCG00040051755.
DR Ensembl; ENSSSCT00045057231; ENSSSCP00045040003; ENSSSCG00045033431.
DR Ensembl; ENSSSCT00050005642; ENSSSCP00050002385; ENSSSCG00050004128.
DR Ensembl; ENSSSCT00055035982; ENSSSCP00055028573; ENSSSCG00055018378.
DR Ensembl; ENSSSCT00060081844; ENSSSCP00060035453; ENSSSCG00060059952.
DR Ensembl; ENSSSCT00065109667; ENSSSCP00065049333; ENSSSCG00065078936.
DR Ensembl; ENSSSCT00065109674; ENSSSCP00065049335; ENSSSCG00065078936.
DR Ensembl; ENSSSCT00070000253; ENSSSCP00070000210; ENSSSCG00070000151.
DR GeneID; 100126291; -.
DR KEGG; ssc:100126291; -.
DR CTD; 4201; -.
DR VGNC; VGNC:103981; MEA1.
DR eggNOG; ENOG502S34Y; Eukaryota.
DR GeneTree; ENSGT00390000016927; -.
DR HOGENOM; CLU_096511_0_0_1; -.
DR InParanoid; Q95313; -.
DR OMA; MGPERIC; -.
DR OrthoDB; 1638941at2759; -.
DR TreeFam; TF332365; -.
DR Proteomes; UP000008227; Chromosome 7.
DR Proteomes; UP000314985; Chromosome 7.
DR Bgee; ENSSSCG00000001655; Expressed in testis and 46 other tissues.
DR ExpressionAtlas; Q95313; baseline and differential.
DR Genevisible; Q95313; SS.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR InterPro; IPR009685; MEA1.
DR PANTHER; PTHR17005; PTHR17005; 1.
PE 2: Evidence at transcript level;
KW Developmental protein; Differentiation; Phosphoprotein; Reference proteome;
KW Spermatogenesis.
FT CHAIN 1..174
FT /note="Male-enhanced antigen 1"
FT /id="PRO_0000096343"
FT REGION 1..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 94..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 103
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q16626"
SQ SEQUENCE 174 AA; 18767 MW; C1BC263E39F29F07 CRC64;
MAAVVLGGDI MGPERIFPNQ TEELGPHQGP TEGTGDWSSE EPEEEQEETG TGPAGYSYQP
LNQDPEQEEV ELAPVGDGED VVADIQDRIQ ALGLHLPDPP LESEDEDEEG ATALSNHSSI
PMDPEHVELV KRTMAGVSLP APGVPAWARE ISDAQWEDVV QKALQARQAT PAWK