MEA1_RAT
ID MEA1_RAT Reviewed; 174 AA.
AC Q5FVH7;
DT 16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 94.
DE RecName: Full=Male-enhanced antigen 1;
DE Short=MEA-1;
GN Name=Mea1; Synonyms=Mea;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-103, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22673903; DOI=10.1038/ncomms1871;
RA Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C.,
RA Olsen J.V.;
RT "Quantitative maps of protein phosphorylation sites across 14 different rat
RT organs and tissues.";
RL Nat. Commun. 3:876-876(2012).
CC -!- FUNCTION: May play an important role in spermatogenesis and/or testis
CC development. {ECO:0000250}.
CC -!- CAUTION: It is uncertain whether Met-1 or Met-11 is the initiator.
CC {ECO:0000305}.
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DR EMBL; CH473987; EDM18839.1; -; Genomic_DNA.
DR EMBL; CH473987; EDM18841.1; -; Genomic_DNA.
DR EMBL; CH473987; EDM18842.1; -; Genomic_DNA.
DR EMBL; CH473987; EDM18843.1; -; Genomic_DNA.
DR EMBL; CH473987; EDM18844.1; -; Genomic_DNA.
DR EMBL; CH473987; EDM18845.1; -; Genomic_DNA.
DR EMBL; BC089978; AAH89978.1; -; mRNA.
DR RefSeq; NP_001037751.1; NM_001044286.1.
DR RefSeq; XP_006244628.1; XM_006244566.3.
DR RefSeq; XP_006244629.1; XM_006244567.3.
DR RefSeq; XP_006244630.1; XM_006244568.3.
DR RefSeq; XP_006244631.1; XM_006244569.3.
DR RefSeq; XP_008765102.1; XM_008766880.1.
DR AlphaFoldDB; Q5FVH7; -.
DR STRING; 10116.ENSRNOP00000023495; -.
DR iPTMnet; Q5FVH7; -.
DR PhosphoSitePlus; Q5FVH7; -.
DR jPOST; Q5FVH7; -.
DR PaxDb; Q5FVH7; -.
DR Ensembl; ENSRNOT00000023495; ENSRNOP00000023495; ENSRNOG00000017144.
DR GeneID; 685131; -.
DR KEGG; rno:685131; -.
DR UCSC; RGD:1597751; rat.
DR CTD; 4201; -.
DR RGD; 1597751; Mea1.
DR eggNOG; ENOG502S34Y; Eukaryota.
DR GeneTree; ENSGT00390000016927; -.
DR HOGENOM; CLU_096511_0_0_1; -.
DR InParanoid; Q5FVH7; -.
DR OrthoDB; 1638941at2759; -.
DR PhylomeDB; Q5FVH7; -.
DR TreeFam; TF332365; -.
DR PRO; PR:Q5FVH7; -.
DR Proteomes; UP000002494; Chromosome 9.
DR Proteomes; UP000234681; Chromosome 9.
DR Bgee; ENSRNOG00000017144; Expressed in testis and 20 other tissues.
DR ExpressionAtlas; Q5FVH7; baseline and differential.
DR Genevisible; Q5FVH7; RN.
DR GO; GO:0005737; C:cytoplasm; ISO:RGD.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR InterPro; IPR009685; MEA1.
DR PANTHER; PTHR17005; PTHR17005; 1.
PE 1: Evidence at protein level;
KW Developmental protein; Differentiation; Phosphoprotein; Reference proteome;
KW Spermatogenesis.
FT CHAIN 1..174
FT /note="Male-enhanced antigen 1"
FT /id="PRO_0000377729"
FT REGION 1..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 95..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 103
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:22673903"
SQ SEQUENCE 174 AA; 18584 MW; C3B16361635B176F CRC64;
MAAVVLGGDT MGPERIFPNQ TEDLGPHQGP TEGTGDWSSE EPEEEQEETG AGPAGYSYQP
LNQDPEQEEV ELAPVGEGED GAADIQDRIQ ALGLHLPDPP LESEDEDEEG AAALSSHSSI
PMDPEHVELV KRTMAGVSLP APGVPAWARE ISDAQWEDVV QKALQARQAS PAWK
