ID   MECA_LACLA              Reviewed;         233 AA.
AC   Q9CEP1;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Adapter protein MecA {ECO:0000255|HAMAP-Rule:MF_01124};
GN   Name=mecA {ECO:0000255|HAMAP-Rule:MF_01124}; OrderedLocusNames=LL1795;
GN   ORFNames=L37085;
OS   Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus.
OX   NCBI_TaxID=272623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IL1403;
RX   PubMed=11337471; DOI=10.1101/gr.gr-1697r;
RA   Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J.,
RA   Ehrlich S.D., Sorokin A.;
RT   "The complete genome sequence of the lactic acid bacterium Lactococcus
RT   lactis ssp. lactis IL1403.";
RL   Genome Res. 11:731-753(2001).
CC   -!- FUNCTION: Enables the recognition and targeting of unfolded and
CC       aggregated proteins to the ClpC protease or to other proteins involved
CC       in proteolysis. {ECO:0000255|HAMAP-Rule:MF_01124}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01124}.
CC   -!- DOMAIN: The N-terminal domain probably binds unfolded/aggregated
CC       proteins; the C-terminal domain interacts with ClpC.
CC   -!- SIMILARITY: Belongs to the MecA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01124}.
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DR   EMBL; AE005176; AAK05893.1; -; Genomic_DNA.
DR   PIR; C86849; C86849.
DR   RefSeq; NP_267952.1; NC_002662.1.
DR   RefSeq; WP_004255173.1; NC_002662.1.
DR   AlphaFoldDB; Q9CEP1; -.
DR   SMR; Q9CEP1; -.
DR   STRING; 272623.L37085; -.
DR   PaxDb; Q9CEP1; -.
DR   EnsemblBacteria; AAK05893; AAK05893; L37085.
DR   GeneID; 60355404; -.
DR   GeneID; 66442782; -.
DR   KEGG; lla:L37085; -.
DR   PATRIC; fig|272623.7.peg.1922; -.
DR   eggNOG; COG4862; Bacteria.
DR   HOGENOM; CLU_071496_2_1_9; -.
DR   OMA; EFFYTVM; -.
DR   Proteomes; UP000002196; Chromosome.
DR   GO; GO:0030674; F:protein-macromolecule adaptor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.70.1950; -; 1.
DR   HAMAP; MF_01124; MecA; 1.
DR   InterPro; IPR038471; MecA_C_sf.
DR   InterPro; IPR008681; Neg-reg_MecA.
DR   PANTHER; PTHR39161; PTHR39161; 1.
DR   Pfam; PF05389; MecA; 1.
DR   PIRSF; PIRSF029008; MecA; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..233
FT                   /note="Adapter protein MecA"
FT                   /id="PRO_0000212270"
SQ   SEQUENCE   233 AA;  27077 MW;  483DAD4E8896A8BD CRC64;
     MKYEDINENT IKITLSFDDL TDYDIKLSDF FGNQEVIEQF FYELVDELGL ENRFGNVGML
     TFQIQPFPQG VHMIVHEEAM LGEGGEIPDD PEEFEELMTG FYNKLNEIGA DMARERGITD
     FKPGLGLPGT KKDEAEQEPD FIYYSIRYED IMSVLTGIKN VKFADEESEF YRYDGNFYLV
     VLDNQKEKGK MHVESTRSRM MEYGEATKMS REFLQEYGEC LIATRALDVL RKI