ID   MECA_LATSS              Reviewed;         229 AA.
AC   Q38VN3;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Adapter protein MecA {ECO:0000255|HAMAP-Rule:MF_01124};
GN   Name=mecA {ECO:0000255|HAMAP-Rule:MF_01124}; OrderedLocusNames=LCA_1448;
OS   Latilactobacillus sakei subsp. sakei (strain 23K) (Lactobacillus sakei
OS   subsp. sakei).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Latilactobacillus.
OX   NCBI_TaxID=314315;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=23K;
RX   PubMed=16273110; DOI=10.1038/nbt1160;
RA   Chaillou S., Champomier-Verges M.-C., Cornet M., Crutz-Le Coq A.-M.,
RA   Dudez A.-M., Martin V., Beaufils S., Darbon-Rongere E., Bossy R., Loux V.,
RA   Zagorec M.;
RT   "The complete genome sequence of the meat-borne lactic acid bacterium
RT   Lactobacillus sakei 23K.";
RL   Nat. Biotechnol. 23:1527-1533(2005).
CC   -!- FUNCTION: Enables the recognition and targeting of unfolded and
CC       aggregated proteins to the ClpC protease or to other proteins involved
CC       in proteolysis. {ECO:0000255|HAMAP-Rule:MF_01124}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01124}.
CC   -!- DOMAIN: The N-terminal domain probably binds unfolded/aggregated
CC       proteins; the C-terminal domain interacts with ClpC.
CC   -!- SIMILARITY: Belongs to the MecA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01124}.
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DR   EMBL; CR936503; CAI55750.1; -; Genomic_DNA.
DR   RefSeq; WP_011375140.1; NC_007576.1.
DR   AlphaFoldDB; Q38VN3; -.
DR   SMR; Q38VN3; -.
DR   STRING; 314315.LCA_1448; -.
DR   EnsemblBacteria; CAI55750; CAI55750; LCA_1448.
DR   KEGG; lsa:LCA_1448; -.
DR   eggNOG; COG4862; Bacteria.
DR   HOGENOM; CLU_071496_2_0_9; -.
DR   OMA; EFFYTVM; -.
DR   OrthoDB; 1678325at2; -.
DR   Proteomes; UP000002707; Chromosome.
DR   GO; GO:0030674; F:protein-macromolecule adaptor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.70.1950; -; 1.
DR   HAMAP; MF_01124; MecA; 1.
DR   InterPro; IPR038471; MecA_C_sf.
DR   InterPro; IPR008681; Neg-reg_MecA.
DR   PANTHER; PTHR39161; PTHR39161; 1.
DR   Pfam; PF05389; MecA; 1.
DR   PIRSF; PIRSF029008; MecA; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..229
FT                   /note="Adapter protein MecA"
FT                   /id="PRO_1000065341"
SQ   SEQUENCE   229 AA;  26578 MW;  D9A4D4300BBF3FDD CRC64;
     MRMEKIDENT IRVLLENDDL EERGITGLDL LSNHKKIERF FYSILEEVDQ DHVFANNDAV
     TFQVLPNEQG LELLISKNLS NLDLNKAQSE MVQGKDGITE YIKDQLLKRD TASSEDDEED
     DEIESYLNQA DNPTKQVVLG FDTFEDWIAL AQQLHIESGV SNLFVYKHQY YAQLVFFLEN
     TTETFVQDDL AVANEFGHKT NYTADFLSEY GQRVMENSAL ELTRYYFKD