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MECA_LISMC
ID   MECA_LISMC              Reviewed;         217 AA.
AC   C1KXE5;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   26-MAY-2009, sequence version 1.
DT   03-AUG-2022, entry version 46.
DE   RecName: Full=Adapter protein MecA {ECO:0000255|HAMAP-Rule:MF_01124};
GN   Name=mecA {ECO:0000255|HAMAP-Rule:MF_01124}; OrderedLocusNames=Lm4b_02217;
OS   Listeria monocytogenes serotype 4b (strain CLIP80459).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=568819;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIP80459;
RX   PubMed=22530965; DOI=10.1186/1471-2164-13-144;
RA   Hain T., Ghai R., Billion A., Kuenne C.T., Steinweg C., Izar B.,
RA   Mohamed W., Mraheil M., Domann E., Schaffrath S., Karst U., Goesmann A.,
RA   Oehm S., Puhler A., Merkl R., Vorwerk S., Glaser P., Garrido P.,
RA   Rusniok C., Buchrieser C., Goebel W., Chakraborty T.;
RT   "Comparative genomics and transcriptomics of lineages I, II, and III
RT   strains of Listeria monocytogenes.";
RL   BMC Genomics 13:144-144(2012).
CC   -!- FUNCTION: Enables the recognition and targeting of unfolded and
CC       aggregated proteins to the ClpC protease or to other proteins involved
CC       in proteolysis. {ECO:0000255|HAMAP-Rule:MF_01124}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01124}.
CC   -!- DOMAIN: The N-terminal domain probably binds unfolded/aggregated
CC       proteins; the C-terminal domain interacts with ClpC.
CC   -!- SIMILARITY: Belongs to the MecA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01124}.
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DR   EMBL; FM242711; CAS05974.1; -; Genomic_DNA.
DR   RefSeq; WP_003724608.1; NC_012488.1.
DR   AlphaFoldDB; C1KXE5; -.
DR   SMR; C1KXE5; -.
DR   PRIDE; C1KXE5; -.
DR   KEGG; lmc:Lm4b_02217; -.
DR   HOGENOM; CLU_071496_2_1_9; -.
DR   OMA; EFFYTVM; -.
DR   BioCyc; LMON568819:LM4B_RS11210-MON; -.
DR   GO; GO:0030674; F:protein-macromolecule adaptor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.70.1950; -; 1.
DR   HAMAP; MF_01124; MecA; 1.
DR   InterPro; IPR038471; MecA_C_sf.
DR   InterPro; IPR008681; Neg-reg_MecA.
DR   PANTHER; PTHR39161; PTHR39161; 1.
DR   Pfam; PF05389; MecA; 1.
DR   PIRSF; PIRSF029008; MecA; 1.
PE   3: Inferred from homology;
FT   CHAIN           1..217
FT                   /note="Adapter protein MecA"
FT                   /id="PRO_1000213625"
SQ   SEQUENCE   217 AA;  25355 MW;  FD6292F1C1095F38 CRC64;
     MEIERINEDT IKFYISYLDL EERGFNQEDV WYDREKSEEL FWDMMDELKY EEEFSPEGPL
     WIQVQALKHG LEVFVTKATI GGKGEDGFDV TLSSPDELAE EKIEKLLEEN FNPVKKEALG
     DDDTLEFILE FRDFEDAISL SRATGLENLV TKLYSYQGKY YLNVEFPENK YDESNIDNAV
     SILLEYGLES NLTGYMLAEY GKVIFDVPAL KQIRKHF
 
 
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