位置:首页 > 蛋白库 > MECA_STAES
MECA_STAES
ID   MECA_STAES              Reviewed;         240 AA.
AC   Q8CPS8;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Adapter protein MecA {ECO:0000255|HAMAP-Rule:MF_01124};
GN   Name=mecA {ECO:0000255|HAMAP-Rule:MF_01124}; OrderedLocusNames=SE_0688;
OS   Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12228 / FDA PCI 1200;
RX   PubMed=12950922; DOI=10.1046/j.1365-2958.2003.03671.x;
RA   Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q.,
RA   Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H.,
RA   Zhao G.-P., Qu D., Danchin A., Wen Y.-M.;
RT   "Genome-based analysis of virulence genes in a non-biofilm-forming
RT   Staphylococcus epidermidis strain (ATCC 12228).";
RL   Mol. Microbiol. 49:1577-1593(2003).
CC   -!- FUNCTION: Enables the recognition and targeting of unfolded and
CC       aggregated proteins to the ClpC protease or to other proteins involved
CC       in proteolysis. {ECO:0000255|HAMAP-Rule:MF_01124}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01124}.
CC   -!- DOMAIN: The N-terminal domain probably binds unfolded/aggregated
CC       proteins; the C-terminal domain interacts with ClpC.
CC   -!- SIMILARITY: Belongs to the MecA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01124}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE015929; AAO04285.1; -; Genomic_DNA.
DR   RefSeq; NP_764243.1; NC_004461.1.
DR   RefSeq; WP_001829308.1; NZ_WBME01000019.1.
DR   AlphaFoldDB; Q8CPS8; -.
DR   SMR; Q8CPS8; -.
DR   STRING; 176280.SE_0688; -.
DR   EnsemblBacteria; AAO04285; AAO04285; SE_0688.
DR   GeneID; 50019172; -.
DR   KEGG; sep:SE_0688; -.
DR   PATRIC; fig|176280.10.peg.662; -.
DR   eggNOG; COG4862; Bacteria.
DR   HOGENOM; CLU_071496_2_1_9; -.
DR   OMA; EFFYTVM; -.
DR   Proteomes; UP000001411; Chromosome.
DR   GO; GO:0030674; F:protein-macromolecule adaptor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.70.1950; -; 1.
DR   HAMAP; MF_01124; MecA; 1.
DR   InterPro; IPR038471; MecA_C_sf.
DR   InterPro; IPR008681; Neg-reg_MecA.
DR   PANTHER; PTHR39161; PTHR39161; 1.
DR   Pfam; PF05389; MecA; 1.
DR   PIRSF; PIRSF029008; MecA; 1.
PE   3: Inferred from homology;
FT   CHAIN           1..240
FT                   /note="Adapter protein MecA"
FT                   /id="PRO_0000212282"
FT   REGION          119..138
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   240 AA;  28716 MW;  631D2D17B32982DF CRC64;
     MRIERVDDTT VKLFITYSDI EARGFSREDL WSNRKRGEEF FWSMMDEINE EEDFVVEGPL
     WIQVHAFEKG VEVTISKSKN EDAMNMSDDD TNHQFDDQVN ELLAQTLEGE ESLEDLFEQR
     KQQKKNHQDK QQRRAHKPSN VRNIIVKFDD LEQVIDYAYH NNQNTDEFED LLYMIDNKYY
     YSIHFDDSVS QEMINDSYSQ LLEFAYPTDK TNIYLNDYAK IIMSHNVTSQ VRKYFTDTNE
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024