ID   MED31_TAESO             Reviewed;         148 AA.
AC   Q8MPD6;
DT   31-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 31;
DE   AltName: Full=Mediator complex subunit 31;
GN   ORFNames=Ts24233;
OS   Taenia solium (Pork tapeworm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC   Eucestoda; Cyclophyllidea; Taeniidae; Taenia.
OX   NCBI_TaxID=6204;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=12076776; DOI=10.1016/s0166-6851(02)00074-9;
RA   Brehm K., Hubert K., Sciutto E., Garate T., Frosch M.;
RT   "Characterization of a spliced leader gene and of trans-spliced mRNAs from
RT   Taenia solium.";
RL   Mol. Biochem. Parasitol. 122:105-110(2002).
CC   -!- FUNCTION: Component of the Mediator complex, a coactivator involved in
CC       the regulated transcription of nearly all RNA polymerase II-dependent
CC       genes. Mediator functions as a bridge to convey information from gene-
CC       specific regulatory proteins to the basal RNA polymerase II
CC       transcription machinery. Mediator is recruited to promoters by direct
CC       interactions with regulatory proteins and serves as a scaffold for the
CC       assembly of a functional preinitiation complex with RNA polymerase II
CC       and the general transcription factors (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the Mediator complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the Mediator complex subunit 31 family.
CC       {ECO:0000305}.
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DR   EMBL; AJ428473; CAD21541.1; -; mRNA.
DR   AlphaFoldDB; Q8MPD6; -.
DR   SMR; Q8MPD6; -.
DR   GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR   GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR   Gene3D; 1.10.10.1340; -; 1.
DR   InterPro; IPR038089; Med31_sf.
DR   InterPro; IPR008831; Mediator_Med31.
DR   PANTHER; PTHR13186; PTHR13186; 1.
DR   Pfam; PF05669; Med31; 1.
PE   2: Evidence at transcript level;
KW   Activator; Nucleus; Transcription; Transcription regulation.
FT   CHAIN           1..148
FT                   /note="Mediator of RNA polymerase II transcription subunit
FT                   31"
FT                   /id="PRO_0000212531"
SQ   SEQUENCE   148 AA;  17306 MW;  B36C5BDA30E938B6 CRC64;
     MQNRPKSVLT PARLGTSGVV RNTLEDPWVR FQIELEFVQS LGNPDYLTFL AQQGCFDKPE
     FINYLSYLQY WKSPSYSRFI TYPFCLHMLD LLQSPDFRRE VAHESVTRFI DDQMLLHWKN
     YLRKRAEMVN KHVQSLDAMA TPGPGPSS