ID   MEDAG_BOVIN             Reviewed;         303 AA.
AC   A4IFN2;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Mesenteric estrogen-dependent adipogenesis protein;
GN   Name=MEDAG;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal muscle;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in processes that promote adipocyte differentiation,
CC       lipid accumulation, and glucose uptake in mature adipocytes.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
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DR   EMBL; BC134670; AAI34671.1; -; mRNA.
DR   RefSeq; NP_001077129.1; NM_001083660.1.
DR   AlphaFoldDB; A4IFN2; -.
DR   STRING; 9913.ENSBTAP00000010884; -.
DR   PaxDb; A4IFN2; -.
DR   PRIDE; A4IFN2; -.
DR   Ensembl; ENSBTAT00000010884; ENSBTAP00000010884; ENSBTAG00000008271.
DR   GeneID; 510187; -.
DR   KEGG; bta:510187; -.
DR   CTD; 84935; -.
DR   VEuPathDB; HostDB:ENSBTAG00000008271; -.
DR   VGNC; VGNC:31371; MEDAG.
DR   eggNOG; ENOG502REG3; Eukaryota.
DR   GeneTree; ENSGT00390000018451; -.
DR   HOGENOM; CLU_080194_0_0_1; -.
DR   InParanoid; A4IFN2; -.
DR   OMA; PGNEVIN; -.
DR   OrthoDB; 1192582at2759; -.
DR   TreeFam; TF328824; -.
DR   Proteomes; UP000009136; Chromosome 12.
DR   Bgee; ENSBTAG00000008271; Expressed in ureter and 98 other tissues.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; ISS:UniProtKB.
DR   InterPro; IPR039230; MEDAG.
DR   InterPro; IPR043460; MEDAG/TEX26.
DR   PANTHER; PTHR33769; PTHR33769; 1.
DR   PANTHER; PTHR33769:SF3; PTHR33769:SF3; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..303
FT                   /note="Mesenteric estrogen-dependent adipogenesis protein"
FT                   /id="PRO_0000350570"
SQ   SEQUENCE   303 AA;  34360 MW;  62F572F31081CFFA CRC64;
     MAGLESAPAA RPSLTSISSG ELRSLWTCDC ELALLPLGQL LRLQPGAFQL RGDQLVVPAP
     AEPASARGGF NVFGDGFVRL DGQLYRLSSY MRRYVELTNY CDYKDYRETI LSKPMLFFVH
     VQTKKDSLKE RTYAFLVNTR HPKIRRQIEQ GMDMVISSVI GESYRLQFDF QEVVKNFFPP
     GNKVVNGEDL SFAYEFKADA LFDFFYWFGL SNSTVKVNGK VLNLSSTSPE KKETIKLFLE
     KMSEPLIRRS SFSDRKFSVT SRGSIDEVFN CNLSPRSSLM EPLVAELPFP CVLESEETPN
     PFI