ID   MEI3_SCHPO              Reviewed;         148 AA.
AC   P08090;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1988, sequence version 1.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=21 kDa protein inducing meiosis and sporulation;
GN   Name=mei3; ORFNames=SPBC119.04;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3034608; DOI=10.1002/j.1460-2075.1987.tb04814.x;
RA   McLeod M., Stein M., Beach D.;
RT   "The product of the mei3+ gene, expressed under control of the mating-type
RT   locus, induces meiosis and sporulation in fission yeast.";
RL   EMBO J. 6:729-736(1987).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: This protein, expressed under control of the mating-type
CC       locus, induces meiosis and sporulation in fission yeast. It down
CC       regulates the ran1/pat1 gene product.
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DR   EMBL; X05142; CAA28788.1; -; Genomic_DNA.
DR   EMBL; CU329671; CAA17919.1; -; Genomic_DNA.
DR   PIR; S07196; S07196.
DR   RefSeq; NP_595285.1; NM_001021192.2.
DR   AlphaFoldDB; P08090; -.
DR   BioGRID; 276608; 13.
DR   IntAct; P08090; 3.
DR   STRING; 4896.SPBC119.04.1; -.
DR   PaxDb; P08090; -.
DR   EnsemblFungi; SPBC119.04.1; SPBC119.04.1:pep; SPBC119.04.
DR   GeneID; 2540070; -.
DR   KEGG; spo:SPBC119.04; -.
DR   PomBase; SPBC119.04; mei3.
DR   VEuPathDB; FungiDB:SPBC119.04; -.
DR   HOGENOM; CLU_1759871_0_0_1; -.
DR   OMA; TERVNNE; -.
DR   PRO; PR:P08090; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0030291; F:protein serine/threonine kinase inhibitor activity; IDA:PomBase.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0140538; P:negative regulation of conjugation with zygote; IMP:PomBase.
DR   GO; GO:0110046; P:signal transduction involved in cell cycle switching, mitotic to meiotic cell cycle; IMP:PomBase.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
PE   4: Predicted;
KW   Meiosis; Reference proteome; Sporulation.
FT   CHAIN           1..148
FT                   /note="21 kDa protein inducing meiosis and sporulation"
FT                   /id="PRO_0000096401"
FT   REGION          1..96
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..67
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   148 AA;  16473 MW;  D358F4524808A856 CRC64;
     MSSQNTSNSR HPASSASALP NRTNTARRST SPRTSTGSSS TNTNTKTVDH AGTTFISSTS
     KRGRSTKAGS VHSVPMKRTK RVRRTPAQRI EHENKENIQT EKVYRIKPVQ RVLSPSDLTN
     ELTILDLFHV PRPNETFDIT DRVNNTSR