MEIG1_DANRE
ID MEIG1_DANRE Reviewed; 92 AA.
AC Q5RGE4; Q5BJJ1;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-JAN-2008, sequence version 2.
DT 03-AUG-2022, entry version 75.
DE RecName: Full=Meiosis expressed gene 1 protein homolog;
GN Name=meig1; ORFNames=si:dkey-153k10.4, zgc:110359;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Olfactory epithelium;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Essential for spermiogenesis. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the MEIG1 family. {ECO:0000305}.
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DR EMBL; BX901962; CAI20678.2; -; Genomic_DNA.
DR EMBL; BC091461; AAH91461.1; -; mRNA.
DR RefSeq; NP_001013488.1; NM_001013470.1.
DR AlphaFoldDB; Q5RGE4; -.
DR SMR; Q5RGE4; -.
DR STRING; 7955.ENSDARP00000121928; -.
DR PaxDb; Q5RGE4; -.
DR Ensembl; ENSDART00000142284; ENSDARP00000121928; ENSDARG00000045705.
DR Ensembl; ENSDART00000150687; ENSDARP00000125368; ENSDARG00000045705.
DR Ensembl; ENSDART00000180751; ENSDARP00000146834; ENSDARG00000115242.
DR Ensembl; ENSDART00000192283; ENSDARP00000144884; ENSDARG00000114008.
DR GeneID; 541343; -.
DR KEGG; dre:541343; -.
DR CTD; 644890; -.
DR ZFIN; ZDB-GENE-050320-33; meig1.
DR eggNOG; ENOG502S7BQ; Eukaryota.
DR GeneTree; ENSGT00390000013550; -.
DR HOGENOM; CLU_160103_0_0_1; -.
DR InParanoid; Q5RGE4; -.
DR OMA; QVKQVDM; -.
DR OrthoDB; 1489247at2759; -.
DR PhylomeDB; Q5RGE4; -.
DR TreeFam; TF329080; -.
DR PRO; PR:Q5RGE4; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 4.
DR Bgee; ENSDARG00000045705; Expressed in testis and 22 other tissues.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR InterPro; IPR020186; Meiosis-expressed_gene_1.
DR PANTHER; PTHR17008; PTHR17008; 1.
DR Pfam; PF15163; Meiosis_expr; 1.
PE 3: Inferred from homology;
KW Differentiation; Reference proteome; Spermatogenesis.
FT CHAIN 1..92
FT /note="Meiosis expressed gene 1 protein homolog"
FT /id="PRO_0000313026"
FT CONFLICT 79
FT /note="C -> S (in Ref. 2; AAH91461)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 92 AA; 11249 MW; 327B541B24E979AC CRC64;
MACAVLLDNN AKPKSMSRAK QWTGEVENLY RFQQAGYRDE LEYRQIKQAE IDRWPDTGFV
KKLQRRDNTF YYYNRKRECE DREVHKVKVY AY