ID   MEMO1_XENTR             Reviewed;         297 AA.
AC   Q6DJ03;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Protein MEMO1;
DE   AltName: Full=Mediator of ErbB2-driven cell motility 1;
DE            Short=Memo-1;
GN   Name=memo1; ORFNames=TGas016p14.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Gastrula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May control cell migration by relaying extracellular
CC       chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2
CC       signaling (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with ERBB2. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MEMO1 family. {ECO:0000305}.
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DR   EMBL; CR762358; CAJ83509.1; -; mRNA.
DR   EMBL; BC075382; AAH75382.1; -; mRNA.
DR   RefSeq; NP_001004925.1; NM_001004925.1.
DR   AlphaFoldDB; Q6DJ03; -.
DR   SMR; Q6DJ03; -.
DR   STRING; 8364.ENSXETP00000063262; -.
DR   PaxDb; Q6DJ03; -.
DR   Ensembl; ENSXETT00000018710; ENSXETP00000018710; ENSXETG00000008547.
DR   GeneID; 448307; -.
DR   KEGG; xtr:448307; -.
DR   CTD; 7795; -.
DR   Xenbase; XB-GENE-5777366; memo1.
DR   eggNOG; KOG3086; Eukaryota.
DR   HOGENOM; CLU_038085_0_1_1; -.
DR   InParanoid; Q6DJ03; -.
DR   OrthoDB; 1057950at2759; -.
DR   Reactome; R-XTR-6785631; ERBB2 Regulates Cell Motility.
DR   Proteomes; UP000008143; Chromosome 5.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000008547; Expressed in testis and 15 other tissues.
DR   CDD; cd07361; MEMO_like; 1.
DR   HAMAP; MF_00055; MEMO1; 1.
DR   InterPro; IPR002737; MEMO1_fam.
DR   PANTHER; PTHR11060; PTHR11060; 1.
DR   Pfam; PF01875; Memo; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..297
FT                   /note="Protein MEMO1"
FT                   /id="PRO_0000260513"
SQ   SEQUENCE   297 AA;  33448 MW;  21234CD5E1CE0B07 CRC64;
     MSNRALCREA SHAGSWYTAS GSQLSAQLDG WLSQAQTSKR PARAIIAPHA GYTYCGSCAA
     HAYKQVDPSV TRRVFILGPS HHVALSRCAL STVDIYRTPL YDLHIDQKVY GDLWKTGMFE
     RMSLQTDEDE HSIEMHLPYT AKTMESHKDD LTIVPVLVGA LSESKEQEFG KLFSKYLADP
     TNLFVISSDF CHWGQRFRYT YYDESQGEIY RSIENLDKMG MGIIEQLDPV QFSNYLKKYH
     NTICGRHPIG VLLNAATELQ KNGVNMSFSF LNYAQSSQCR SWQDSSVSYA AGALVVH