ID   MENE_GEOKA              Reviewed;         490 AA.
AC   Q5KVX9;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=2-succinylbenzoate--CoA ligase {ECO:0000255|HAMAP-Rule:MF_00731};
DE            EC=6.2.1.26 {ECO:0000255|HAMAP-Rule:MF_00731};
DE   AltName: Full=o-succinylbenzoyl-CoA synthetase {ECO:0000255|HAMAP-Rule:MF_00731};
DE            Short=OSB-CoA synthetase {ECO:0000255|HAMAP-Rule:MF_00731};
GN   Name=menE {ECO:0000255|HAMAP-Rule:MF_00731}; OrderedLocusNames=GK2872;
OS   Geobacillus kaustophilus (strain HTA426).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus;
OC   Geobacillus thermoleovorans group.
OX   NCBI_TaxID=235909;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HTA426;
RX   PubMed=15576355; DOI=10.1093/nar/gkh970;
RA   Takami H., Takaki Y., Chee G.-J., Nishi S., Shimamura S., Suzuki H.,
RA   Matsui S., Uchiyama I.;
RT   "Thermoadaptation trait revealed by the genome sequence of thermophilic
RT   Geobacillus kaustophilus.";
RL   Nucleic Acids Res. 32:6292-6303(2004).
CC   -!- FUNCTION: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA
CC       (OSB-CoA). {ECO:0000255|HAMAP-Rule:MF_00731}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2-succinylbenzoate + ATP + CoA = 2-succinylbenzoyl-CoA + AMP +
CC         diphosphate; Xref=Rhea:RHEA:17009, ChEBI:CHEBI:18325,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:57364, ChEBI:CHEBI:456215; EC=6.2.1.26;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00731};
CC   -!- PATHWAY: Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate
CC       biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 5/7.
CC       {ECO:0000255|HAMAP-Rule:MF_00731}.
CC   -!- PATHWAY: Quinol/quinone metabolism; menaquinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00731}.
CC   -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC       MenE subfamily. {ECO:0000255|HAMAP-Rule:MF_00731}.
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DR   EMBL; BA000043; BAD77157.1; -; Genomic_DNA.
DR   RefSeq; WP_011232344.1; NC_006510.1.
DR   AlphaFoldDB; Q5KVX9; -.
DR   SMR; Q5KVX9; -.
DR   STRING; 235909.GK2872; -.
DR   EnsemblBacteria; BAD77157; BAD77157; GK2872.
DR   KEGG; gka:GK2872; -.
DR   eggNOG; COG0318; Bacteria.
DR   HOGENOM; CLU_000022_59_7_9; -.
DR   OMA; WLMQRAF; -.
DR   UniPathway; UPA00079; -.
DR   UniPathway; UPA01057; UER00166.
DR   Proteomes; UP000001172; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008756; F:o-succinylbenzoate-CoA ligase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009234; P:menaquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; -; 1.
DR   HAMAP; MF_00731; MenE; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR010192; MenE.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   TIGRFAMs; TIGR01923; menE; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Ligase; Menaquinone biosynthesis; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..490
FT                   /note="2-succinylbenzoate--CoA ligase"
FT                   /id="PRO_1000045964"
SQ   SEQUENCE   490 AA;  54012 MW;  D454FADF55B9C7A2 CRC64;
     MTTMPNWLKQ RAFLTPERIA VSDGRRTKTF AELYEAAAVW ARRLAQAGVK EGDIVALLMK
     NRIEMIEIIH ALFFLGARVL LQNVRLTSYE LGWQLDDSGA RLAIADEELA GSLDGDGRVL
     TVGAVAALPE VDVSLKETCD LEEVATIMYT SGTTGTPKGV LQTYGNHWWS AVGSALNLGL
     HERDCWLAAV PLFHISGLSI AMRSVIYGMP MRLQTSFDPK EANEWIMRGD VTIMSVVAAM
     LQRMVAELGE ARYPDTFRCM LLGGGPAPRP LLEACKEKGI PVYQTYGMTE TASQIATLAP
     EYSLTKLGSA GKPLFPAELC ILKDGKPAAP HEAGEIVVKG PNVTKGYWQR PEATAQAIRG
     GWFFTGDIGY LDEDGFLYVL DRRSDLIISG GENVYPAEVE AVLLSHPDVE EAGVTGVENE
     TWGQVPYAFV RLKRGASPDE AALRAFCRER LAKYKVPARI YFVDELPRNA AQKLLRRELK
     RLIPKTEQTF